A9420
6-乙酰-7-脱乙酰福斯考灵
from Coleus forskohlii, ≥98%
别名:
6β-乙酰氧基-1α,7β,9α-三羟基-8,13-环氧-异佛司可林-14-烯-11-酮, 异佛司可林
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关于此项目
经验公式（希尔记法）:
C22H34O7
化学文摘社编号:
分子量:
410.50
UNSPSC Code:
41116107
PubChem Substance ID:
MDL number:
biological source
Coleus forskohlii
assay
≥98%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
storage temp.
−20°C
SMILES string
CC(=O)O[C@@H]1[C@H](O)[C@@]2(C)O[C@](C)(CC(=O)[C@]2(O)[C@@]3(C)[C@@H](O)CCC(C)(C)C13)C=C
InChI
1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(28-12(2)23)17(26)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16?,17-,19-,20-,21+,22-/m0/s1
InChI key
CLOQVZCSBYBUPB-VDCUXWMXSA-N
Biochem/physiol Actions
具有正性肌力和腺苷酸环化酶激活特性的抗高血压药
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Bhat, S.V., et al.
Tetrahedron Letters, 1669-1669 (1977)
S V Bhat et al.
Journal of medicinal chemistry, 26(4), 486-492 (1983-04-01)
Four naturally occurring analogues of forskolin were isolated. Forty-nine semisynthetic derivatives were prepared, incorporating structural alterations at the 1-, 6-, 7-, 9-, 11-, and 14/15-positions. Blood pressure lowering properties of 53 compounds were assessed in anesthetized normotensive cats and of
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