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Merck
CN

A9630

4-雄烯-3,17-二酮

≥98%

别名:

雄烯二酮

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关于此项目

经验公式(希尔记法):
C19H26O2
化学文摘社编号:
分子量:
286.41
EC Number:
200-554-5
UNSPSC Code:
51111800
PubChem Substance ID:
Beilstein/REAXYS Number:
2059239
MDL number:
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InChI key

AEMFNILZOJDQLW-QAGGRKNESA-N

InChI

1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=O)CC[C@@]24[H]

assay

≥98%

drug control

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

mp

170-171 °C (lit.)

Gene Information

human ... HSD17B3(3293)

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Biochem/physiol Actions

睾酮前体和具有雄激素活性的代谢物。
睾酮前体和具有雄激素活性的代谢物;可增大前列腺癌或胰腺癌的风险。

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Lact. - Repr. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Floriane Guibert et al.
Proceedings. Biological sciences, 280(1753), 20122368-20122368 (2012-12-21)
The prenatal environment is a source of phenotypic variability influencing the animal's characteristics. Prenatal stress affects not only the development of offspring, but also that of the following generation. Such effects have been best documented in mammals but can also
D S King et al.
JAMA, 281(21), 2020-2028 (1999-06-08)
Androstenedione, a precursor to testosterone, is marketed to increase blood testosterone concentrations as a natural alternative to anabolic steroid use. However, whether androstenedione actually increases blood testosterone levels or produces anabolic androgenic effects is not known. To determine if short-
P S Feldman et al.
Cancer, 49(4), 714-721 (1982-02-15)
A 51-year-old man had a malignant Leydig cell tumor of the testis with elevation of serum estrone and androstenedione as well as urine chorionic gonadotropin. The fine structural features of the neoplasm resembled those of nontumorous Leydig cells as well
R S Riikonen
Journal of child neurology, 11(5), 383-388 (1996-09-01)
Infants with cryptogenic infantile spasms seem to differ from those with symptomatic spasms in having a higher cerebrospinal fluid corticotropin content, different levels of corticotropin release after exogenous vasopressin, higher serum levels of progesterone, higher dehydroepiandrosterone: androstenedione ratio (during corticotropin
A Mouritsen et al.
The Journal of clinical endocrinology and metabolism, 98(9), 3755-3764 (2013-07-05)
Little is known about the possible deleterious effects of phthalate exposure on endogenous sex steroid levels in children. Our objective was to investigate whether urinary phthalate metabolite levels are associated with circulating adrenal androgen levels and age at puberty. This

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