biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
AP2b 1F3/8, monoclonal
form
buffered aqueous solution
mol wt
antigen ~50 kDa
species reactivity
human
concentration
~1 mg/mL
technique(s)
indirect ELISA: suitable, western blot: 5-10 μg/mL using U87total cell extract
isotype
IgG2a
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... TFAP2B(7021)
General description
Adaptor protein-2 (AP2) is a key constituent of clathrin-coated vesicles that mediates the endocytosis of cell membrane components such as G protein-coupled receptors (GPCRs). AP2 is a heterotetramer that consists of α, β, μ and σ subunits which bind to tyrosine- and dileucine-based motifs on membrane-associated cargo proteins.
Mouse Monoclonal Anti-AP-2β antibody recognizes human AP-2β.
Mouse Monoclonal Anti-AP-2β antibody recognizes human AP-2β.
Immunogen
truncated human AP-2β recombinant protein.
Application
Mouse Monoclonal Anti-AP-2beta antibody can be used for western blot (5-10 μg/ml) and indirect ELISA.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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12 - Non Combustible Liquids
flash_point_f
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flash_point_c
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ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
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Tomasz Szul et al.
Cellular logistics, 1(2), 69-76 (2011-06-21)
Surface delivery of proteins involved in cell-cell and cell-matrix interactions in cultured mammalian cells requires the GBF1 guanine nucleotide exchange factor. However, the role of GBF1 in delivery of adhesion proteins during organogenesis in intact animals has not been characterized.
M Andrew Nesbit et al.
Nature genetics, 45(1), 93-97 (2012-12-12)
Adaptor protein-2 (AP2), a central component of clathrin-coated vesicles (CCVs), is pivotal in clathrin-mediated endocytosis, which internalizes plasma membrane constituents such as G protein-coupled receptors (GPCRs). AP2, a heterotetramer of α, β, μ and σ subunits, links clathrin to vesicle