AV100639
Anti-FOS antibody produced in rabbit
IgG fraction of antiserum
别名:
Anti-v-fos FBJ murine osteosarcoma viral oncogene homolog
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关于此项目
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
41 kDa
species reactivity
mouse, human, sheep, bovine, rat, dog, pig
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... FOS(2353)
General description
c-Fos is an inducible transcription factor and a functional marker of activated neurons. It is induced in response to neurotransmitters and growth factors.
Immunogen
Synthetic peptide directed towards the C terminal region of human FOS
Application
Anti-FOS produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.
Biochem/physiol Actions
c-Fos is a trans-acting factor that does not directly bind DNA. It interacts with AP-1 transcription factor, a step that is prerequisite for c-Fos-mediated gene expression. The role of c-Fos has been studied in activation of neurons, oncogenesis and inflammation of bone and skin.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: CTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLA
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
R Chiu et al.
Cell, 54(4), 541-552 (1988-08-12)
Cell lines stably transfected with metal inducible, MT-fos chimeric genes were used to study the ability of the c-fos gene product, Fos, to act as a transcriptional trans-activator. In 3T3MTfos cells, induction of Fos expression led to specific trans-activation of
K J Kovács
Neurochemistry international, 33(4), 287-297 (1998-12-05)
This article summarizes the achievements that have been accumulated about the role of c-Fos as a transcription factor and as a functional marker of activated neurons. Since its discovery, more than a decade ago, as an inducible immediate-early gene encoding
Rainer Zenz et al.
Arthritis research & therapy, 10(1), 201-201 (2008-01-30)
Activator protein 1 (AP-1) (Fos/Jun) is a transcriptional regulator composed of members of the Fos and Jun families of DNA binding proteins. The functions of AP-1 were initially studied in mouse development as well as in the whole organism through
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