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Merck
CN

AV100748

Sigma-Aldrich

Anti-MyBL2 antibody produced in rabbit

affinity isolated antibody

别名:

Anti-v-Myb myeloblastosis viral oncogene homolog (avian)-like 2

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UNSPSC代码:
12352203
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生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

分子量

79 kDa

种属反应性

guinea pig, rat, rabbit, human, bovine, zebrafish, horse, canine

浓度

0.5 mg - 1 mg/mL

技术

immunohistochemistry: suitable
western blot: suitable

NCBI登记号

UniProt登记号

储存温度

−20°C

基因信息

human ... MYBL2(4605)

一般描述

Myb-related protein B/v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 (MyBL2), a MYB family member, is a transcription factor involved in the regulation of cyclin A/cyclin-dependent kinase 2-dependent cell cycle progression. MyBL2 is implicated in the development and maintenance of the stem cell phenotype with a role in the proliferation and differentiation of several cell types. MYBL2 plays a subtle but key role in linking specific aspects of cell-cycle progression with generation of signals for differentiation. MYBL2 is implicated in human malignancies such as hepatocellular carcinoma (HCC).
Rabbit polyclonal anti-MyBL2 antibody reacts with canine, rat, zebrafish, bovine, chicken, and human Myb-related protein B/v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 transcription factors.

免疫原

The immunogen for anti-MYBL2 antibody: synthetic peptide derected towards the N terminal of human MYBL2

应用

Anti-MyBL2 antibody produced in rabbit is suitable for western blotting at a working concentration of 0.5-1.0 μg/ml. A concentration of 4-8 μg/ml may be used for immunohistochemistry of paraffin-embedded tissue sections.
Rabbit polyclonal anti-MyBL2 antibody is used to tag Myb-related protein B/v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of myb-related protein B/v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 in cell-cycle progression and differentiation.

外形

Lyophilized from PBS buffer with 2% sucrose

其他说明

Synthetic peptide located within the following region: RCEDLDELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWK

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

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Lung adenocarcinoma (LUAD) is the most common form of malignant tumor and closely correlated with high risk of death worldwide. Accumulating researches have manifested that long noncoding RNAs (lncRNAs) are deeply involved in the progression of multiple cancers. LncRNA LOXL1
Guo-Jun Geng et al.
Experimental and therapeutic medicine, 15(2), 1633-1639 (2018-02-13)
Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer mortality worldwide. A growing body of evidence indicates that microRNA (miR) have important and diverse roles in the proliferation, apoptosis and metastasis of human cancer cells. In the

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