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Merck
CN

AV100748

Anti-MyBL2 antibody produced in rabbit

affinity isolated antibody

别名:

Anti-v-Myb myeloblastosis viral oncogene homolog (avian)-like 2

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UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

mol wt

79 kDa

species reactivity

guinea pig, rat, rabbit, human, bovine, zebrafish, horse, canine

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... MYBL2(4605)

General description

Myb-related protein B/v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 (MyBL2), a MYB family member, is a transcription factor involved in the regulation of cyclin A/cyclin-dependent kinase 2-dependent cell cycle progression. MyBL2 is implicated in the development and maintenance of the stem cell phenotype with a role in the proliferation and differentiation of several cell types. MYBL2 plays a subtle but key role in linking specific aspects of cell-cycle progression with generation of signals for differentiation. MYBL2 is implicated in human malignancies such as hepatocellular carcinoma (HCC).
Rabbit polyclonal anti-MyBL2 antibody reacts with canine, rat, zebrafish, bovine, chicken, and human Myb-related protein B/v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 transcription factors.

Immunogen

The immunogen for anti-MYBL2 antibody: synthetic peptide derected towards the N terminal of human MYBL2

Application

Anti-MyBL2 antibody produced in rabbit is suitable for western blotting at a working concentration of 0.5-1.0 μg/ml. A concentration of 4-8 μg/ml may be used for immunohistochemistry of paraffin-embedded tissue sections.
Rabbit polyclonal anti-MyBL2 antibody is used to tag Myb-related protein B/v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of myb-related protein B/v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 in cell-cycle progression and differentiation.

Physical form

Lyophilized from PBS buffer with 2% sucrose

Other Notes

Synthetic peptide located within the following region: RCEDLDELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWK

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Wei Li et al.
Cancer medicine, 9(2), 689-699 (2019-11-24)
Lung adenocarcinoma (LUAD) is the most common form of malignant tumor and closely correlated with high risk of death worldwide. Accumulating researches have manifested that long noncoding RNAs (lncRNAs) are deeply involved in the progression of multiple cancers. LncRNA LOXL1
Guo-Jun Geng et al.
Experimental and therapeutic medicine, 15(2), 1633-1639 (2018-02-13)
Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer mortality worldwide. A growing body of evidence indicates that microRNA (miR) have important and diverse roles in the proliferation, apoptosis and metastasis of human cancer cells. In the

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