生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
38 kDa
种属反应性
human, dog, rabbit, guinea pig, mouse, rat
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... E2F5(1875)
一般描述
The members of E2F family of transcription factors bind to promoter regions and regulate cell proliferation.
免疫原
Synthetic peptide directed towards the N terminal region of human E2F5
应用
Anti-E2F5 antibody produced in rabbit is suitable for western blotting at a concentration of 0.4 μg/ml.
生化/生理作用
Overexpression of E2F5 has been reported in solid tumors of breast, ovarian, colon and hepatocellular carcinoma. It is a transcription repressor with regulatory roles in cell proliferation, growth and cell cycle progression.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: KAEIEDLELKERELDQQKLLLQQSIKNVMDDSINNRFSYVTHEDICNCFN
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
A potential oncogenic role of the commonly observed E2F5 overexpression in hepatocellular carcinoma.
Yuzhu Jiang et al.
World journal of gastroenterology, 17(4), 470-477 (2011-01-29)
To explore the expression pattern of E2F5 in primary hepatocellular carcinomas (HCCs) and elucidate the roles of E2F5 in hepatocarcinogenesis. E2F5 expression was analyzed in 120 primary HCCs and 29 normal liver tissues by immunohistochemistry analysis. E2F5-small interfering RNA was
Alicia Subtil-Rodríguez et al.
Nucleic acids research, 42(4), 2185-2196 (2013-11-23)
The precise regulation of S-phase-specific genes is critical for cell proliferation. How the repressive chromatin configuration mediated by the retinoblastoma protein and repressor E2F factors changes at the G1/S transition to allow transcription activation is unclear. Here we show ChIP-on-chip
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