生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
27 kDa
种属反应性
mouse, rat, human, bovine, dog
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... HOXC6(3223)
免疫原
Synthetic peptide directed towards the C terminal region of human HOXC6
应用
Anti-HOXC6 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5 μg/ml.
生化/生理作用
HOXC6 belongs to the homeoprotein family of transcription factors that regulate morphogenesis and differentiation during embryonic development. Extensive crosstalk between HOXC6 and Wnt, Notch and PI3Kpathways has been observed in prostate cancer progression. HOXC6 also modulates the expression of Bcl-2 and regulates anti-apoptotic pathway in human head and neck squamous cell carcinoma.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: KIWFQNRRMKWKKESNLTSTLSGGGGGATADSLGGKEEKREETEEEKQKE
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Carlos S Moreno
The American journal of pathology, 176(2), 518-527 (2009-12-19)
The transforming growth factor beta, Hedgehog, Notch, and Wnt signaling pathways all play critical roles in the development and progression of prostate cancer. It is becoming increasingly apparent that these pathways may intersect with developmentally important transcription factors such as
Sung-Min Moon et al.
The Journal of biological chemistry, 287(42), 35678-35688 (2012-08-17)
Homeobox C6 (HOXC6) genes belong to the homeoprotein family of transcription factors, which play an important role in morphogenesis and cellular differentiation during embryonic development. The aim of this study was to explore the role of HOXC6 in the regulation
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