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Merck
CN

AV31377

Sigma-Aldrich

Anti-FOSL1 antibody produced in rabbit

affinity isolated antibody

别名:

Anti-FOS-like antigen 1, Anti-FRA1, Anti-Fra-1

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UNSPSC代码:
12352203
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生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

分子量

29 kDa

种属反应性

human, zebrafish, rat, bovine, canine, rabbit, mouse, guinea pig, horse, sheep

浓度

0.5 mg - 1 mg/mL

技术

immunohistochemistry: suitable
western blot: suitable

NCBI登记号

UniProt登记号

储存温度

−20°C

基因信息

human ... FOSL1(8061)

一般描述

FOSL1 has been identified as a transcriptional target of c-Fos during the differentiation of osteoclasts. Furthermore, FOSL1 functions as a downstream effector of PI3K/AKT signaling and regulates trophoblast development during the establishment of maternal-fetal interfaces.
Rabbit Anti-FOSL1 antibody recognizes bovine, human, mouse, rat, and canine FOSL1.

免疫原

The immunogen for anti-FOSL1 antibody: synthetic peptide derected towards the middle region of human FOSL1

应用

Rabbit Anti-FOSL1 antibody can be used for western blot ( 0.5μg/ml) and immunohistochemical (4-8μg/ml) assays.

外形

Lyophilized from PBS buffer with 2% sucrose

其他说明

Synthetic peptide located within the following region: TDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAK

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hana Janouskova et al.
Nature medicine, 23(9), 1046-1054 (2017-08-15)
It is generally assumed that recurrent mutations within a given cancer driver gene elicit similar drug responses. Cancer genome studies have identified recurrent but divergent missense mutations affecting the substrate-recognition domain of the ubiquitin ligase adaptor SPOP in endometrial and
K Matsuo et al.
Nature genetics, 24(2), 184-187 (2000-02-02)
Osteoclasts are bone-resorbing cells derived from haematopoietic precursors of the monocyte-macrophage lineage. Mice lacking Fos (encoding c-Fos) develop osteopetrosis due to an early differentiation block in the osteoclast lineage. c-Fos is a component of the dimeric transcription factor activator protein-1
Lindsey N Kent et al.
Molecular and cellular biology, 31(23), 4801-4813 (2011-09-29)
Remodeling of uterine spiral arteries by trophoblast cells is a requisite process for hemochorial placentation and successful pregnancy. The rat exhibits deep intrauterine trophoblast invasion and accompanying trophoblast-directed vascular modification. The involvement of phosphatidylinositol 3 kinase (PI3K), AKT, and Fos-like
Li-Li Zhao et al.
Neural regeneration research, 18(9), 2056-2066 (2023-03-18)
The key regulators and regeneration-associated genes involved in axonal regeneration of neurons after injury have not been clarified. In high-throughput sequencing, various factors influence the final sequencing results, including the number and size of cells, the depth of sequencing, and
Chunyan Zhao et al.
Cancer research, 74(14), 3983-3994 (2014-05-17)
Triple-negative breast cancer (TNBC) is an aggressive clinical subtype accounting for up to 20% of all breast cancers, but its malignant determinants remain largely undefined. Here, we show that in TNBC the overexpression of Fra-1, a component of the transcription

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