biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
mol wt
31 kDa
species reactivity
mouse, horse, guinea pig, sheep, canine, rat, zebrafish, rabbit, human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... TPM1(7168)
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General description
TropoMyosin 1 (α) (TPM1, CMH3, TMSA, TPM1) is an α-helical polypeptide involved in the stabilization of actin filament components of the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM1 in association with the troponin complex regulates calcium-dependent interaction of actin and myosin during muscle contraction. Defective TPM1 is associated with muscle diseases such as hypertrophic cardiomyopathy.
Immunogen
The immunogen for anti-TPM1 antibody: synthetic peptide derected towards the N terminal of human TPM1
Application
Anti-TPM1 polyclonal antibody is used to tag tropomyosin 1 (α) protein for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of tropomyosin 1 (α) in muscle contraction.
Biochem/physiol Actions
Anti-TPM1 polyclonal antibody reacts with zebrafish, human, mouse, rat, and canine tropomyosin 1-α proteins.
Physical form
Lyophilized from PBS buffer with 2% sucrose
Other Notes
Synthetic peptide located within the following region: DRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQE
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
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