Anti-AMOTL2 antibody produced in rabbit

Angiomotin-like protein 2, a member of the motins protein family, is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. AMOTL2 regulates γAP1 cytoplasm-to-nucleus translocation through direct protein-protein interaction. γAP1 is a component of the Hippo pathway involved in controlling organ size via regulation of cell proliferation and apoptosis.

synthetic peptide corresponding to a region of human AMOTL2 with an internal ID of P11130

Anti-Angiomotin-like protein 2 antibody is used to tag Angiomotin-like protein 2 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of Angiomotin-like protein 2 in the regulation of gene expression, cell proliferation, apoptosis and angiogenesis.

Anti- AMOTL2 polyclonal antibody reacts with mouse, canine, and human angiomotin-like protein 2.

Lyophilized from PBS buffer with 2% sucrose

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