AV45752
Anti-SOD1 antibody produced in rabbit
IgG fraction of antiserum
别名:
Anti-ALS, Anti-ALS1, Anti-Homodimer, Anti-IPOA, Anti-SOD, Anti-SuPeroxide dismutase 1, soluble (aMyotrophic lateral sclerosis 1 (adult))
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
mol wt
16 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... SOD1(6647)
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General description
Superoxide dismutase 1, soluble (aMyotrophic lateral sclerosis 1 (adult)) (SOD1, ALS1, ALS, IPOA, SOD) is a copper-zinc enzyme that destroys free superoxide radicals in the cytoplasm and mitochondrial inter-membrane space of cells. Mutated SOD1 is linked to familial amyotrophic lateral sclerosis (ALS).
Immunogen
The immunogen for anti-SOD1 antibody: synthetic peptide derected towards the N terminal of human SOD1
Application
Anti-SOD1 polyclonal antibody is used to tag superoxide dismutase 1 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of superoxide dismutase 1 in cellular oxidative stress defense and as a causative agent in familial amyotrophic lateral sclerosis (ALS).
Biochem/physiol Actions
Anti-SOD1 polyclonal antibody reacts with human superoxide dismutase 1.
Physical form
Lyophilized from PBS buffer with 2% sucrose
Other Notes
Synthetic peptide located within the following region: MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHE
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
K Marosi et al.
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Lijun Wang et al.
Neurobiology of disease, 71, 317-324 (2014-08-20)
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