AV46009
Anti-NCF4 antibody produced in rabbit
affinity isolated antibody
别名:
Ncf4 Antibody, Ncf4 Antibody - Anti-NCF4 antibody produced in rabbit, Anti-MGC3810, Anti-NCF, Anti-Neutrophil cytosolic factor 4, 40 kDa, Anti-P40PHOX, Anti-SH3PXD4
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
39 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... NCF4(4689)
General description
The previously assigned protein identifier A8K4F9 has been merged into Q15080. Full details can be found on the UniProt database.
Immunogen
Synthetic peptide directed towards the N terminal region of human NCF4
Application
Anti-NCF4 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml.
Biochem/physiol Actions
Anti-NCF4 antibody produced in rabbit is also referred as Anti-Neutrophil cytosolic factor 4, 40kDa, Anti-SH3PXD4 or Anti-P40PHOX.
P40PHOX is a cytosolic component of the activation complex NADPH oxidase that regulates membrane translocation of p67phox and p47phox through the PB1-PC interaction. It facilitates production of superoxide, a multicomponent enzyme system important for host defense. The Px domain of the protein interacts with lipid products of PI3K proposes its role in PI3 kinase-mediated signaling pathway.
P40PHOX is a cytosolic component of the activation complex NADPH oxidase that regulates membrane translocation of p67phox and p47phox through the PB1-PC interaction. It facilitates production of superoxide, a multicomponent enzyme system important for host defense. The Px domain of the protein interacts with lipid products of PI3K proposes its role in PI3 kinase-mediated signaling pathway.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: SKYLIYRRYRQFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQE
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase.
Futoshi Kuribayashi et al.
The EMBO journal, 21(23), 6312-6320 (2002-11-29)
Activation of the superoxide-producing phagocyte NADPH oxidase, crucial in host defense, requires the cytosolic proteins p67(phox) and p47(phox). They translocate to the membrane upon cell stimulation and activate flavocytochrome b(558), the membrane-integrated catalytic core of this enzyme system. The activators
F Kanai et al.
Nature cell biology, 3(7), 675-678 (2001-07-04)
PX domains are found in a variety of proteins that associate with cell membranes, but their molecular function has remained obscure. We show here that the PX domains in p47phox and p40phox subunits of the phagocyte NADPH oxidase bind to
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持