AV46845
Anti-TMED3 antibody produced in rabbit
IgG fraction of antiserum
别名:
Anti-C15orf22, Anti-MGC133022, Anti-P24B, Anti-Transmembrane emp24 protein transport domain containing 3
生物来源
rabbit
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
25 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... TMED3(23423)
免疫原
Synthetic peptide directed towards the C terminal region of human TMED3
应用
Anti-TMED3 antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/mL.
生化/生理作用
TMED3 (transmembrane emp24 protein transport domain containing 3) gene encodes for single-pass type I membrane protein that belongs to EMP24/GP25L family. It plays a crucial role in vesicular protein trafficking, mainly in the early secretory pathway as well as assists in coupled localization of TMED2 and TMED10 in the cis-Golgi network. P24 protein bind to coat proteins of COPI and COPII vesicles and may facilitate the vesicle biogenesis, cargo uptake and quality control.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: DRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPISRAVHS
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
G Emery et al.
Journal of cell science, 113 ( Pt 13), 2507-2516 (2000-06-15)
Recent studies show that small trans-membrane proteins of approximately 22-24 kDa (the p24 family), which are grouped into 4 sub-families by sequence homology (p23, p24, p25 and p26), are involved in the early secretory pathway. In this study, we have
Nicole Jenne et al.
The Journal of biological chemistry, 277(48), 46504-46511 (2002-09-19)
The p24 proteins belong to a highly conserved family of membrane proteins that cycle in the early secretory pathway. They bind to the coat proteins of COPI and COPII vesicles, and are proposed to be involved in vesicle biogenesis, cargo
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