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Merck
CN

AV47546

Sigma-Aldrich

Anti-UNCX antibody produced in rabbit

affinity isolated antibody

别名:

Anti-UNCX4.1

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UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

54 kDa

种属反应性

human

浓度

0.5 mg - 1 mg/mL

技术

immunohistochemistry: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... UNCX(340260)

一般描述

UNCX is a homeobox transcription factor that regulates the survival and proliferation of neuronal cells in the olfactory epithelium. Studies in Xenopus laevis have revealed that UNCX is expressed in the pharyngeal pouch and sclerotome.
Rabbit Anti-UNCX antibody recognizes human, and zebrafish UNCX.

免疫原

Synthetic peptide directed towards the C terminal region of human UNCX

应用

Rabbit Anti-UNCX antibody is suitable for western blot applications at a concentration of 1μg/ml and for immunohistochemistry applications at 4-8μg/ml.

生化/生理作用

UNCX is a transcription factor involved in somitogenesis and neurogenesis. It is required for the maintenance and differentiation of particular elements of the axial skeleton. It may act upstream of PAX9. UNCX plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

其他说明

Synthetic peptide located within the following region: AAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPG

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Romel Sebastián Sánchez et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 242(5), 572-579 (2013-02-13)
The axial skeleton develops from the sclerotome, a mesenchymal cell population derived from somites. Sclerotomal cells migrate from somites to the perinotochordal and perineural space where they differentiate into chondrocytes to form cartilage and bone. In anurans, little is known
Giulia Daniele et al.
Haematologica, 102(7), 1204-1214 (2017-04-16)
We here describe a leukemogenic role of the homeobox gene
Neeraja Sammeta et al.
Molecular and cellular neurosciences, 45(4), 398-407 (2010-08-10)
Uncx (Phd1, Chx4) is a paired homeobox transcription factor gene. It and its probable functional partners, Tle co-repressors, were expressed by neurally-fated basal progenitor cells and olfactory sensory neurons of the olfactory epithelium. Uncx expression was rare in olfactory epithelia

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