AV50225
Anti-SLAMF6 (AB2) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-KALI, Anti-KALIb, Anti-Ly108, Anti-MGC104953, Anti-NTB-A, Anti-NTBA, Anti-SF2000, Anti-SLAM family member 6
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
34 kDa
species reactivity
human
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... SLAMF6(114836)
Immunogen
Synthetic peptide directed towards the N terminal region of human SLAMF6
Application
Anti-SLAMF6 (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
Biochem/physiol Actions
SLAM family member 6 (SLAMF6) is a type I transmembrane protein that is involved in natural killer (NK) cell activation in association with SH2 domain-containing phosphatases (SHPs). It is expressed on NK, T and B cells.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: EIHVTNPKQGKRLNFTQSYSLQLSNLKMEDTGSYRAQISTKTSAKLSSYT
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Laurence Menard et al.
The Journal of allergy and clinical immunology, 133(4), 1149-1161 (2014-01-01)
Signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) can mediate the function of SLAM molecules, which have been proposed to be involved in the development of autoimmunity in mice. We sought to determine whether the SLAM/SAP pathway regulates the establishment of
Timothy J Wilson et al.
PloS one, 9(3), e92184-e92184 (2014-03-20)
SLAM family receptors regulate activation and inhibition in immunity through recruitment of activating and inhibitory SH2 domain containing proteins to immunoreceptor tyrosine based switch motifs (ITSMs). Binding of the adaptors, SAP and EAT-2 to ITSMs in the cytoplasmic regions of
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