生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
36 kDa
种属反应性
horse, rat, bovine, human, mouse, guinea pig, rabbit
浓度
0.5 mg - 1 mg/mL
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... HELT(391723)
免疫原
Synthetic peptide directed towards the middle region of human HELT
应用
Anti-HELT antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
生化/生理作用
Helt bHLH transcription factor (HELT) is a transcriptional repressor mainly expressed in undifferentiated neural progenitors in some developing brain regions. It is involved in neuronal differentiation and determination of neuronal identity. HELT acts as selector gene and determines the GABAergic or glutamatergic fate of the neurons.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: EMTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTV
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Tomoyuki Uchida et al.
Experimental hematology, 42(5), 369-379 (2014-02-04)
We have previously shown that elevated expression of Hairy enhancer of split 1 (Hes1) contributes to blast crisis transition in Bcr-Abl-positive chronic myelogenous leukemia. Here we investigate whether Hes1 is involved in the development of other myeloid neoplasms. Notably, Hes1
Tomoya Nakatani et al.
Development (Cambridge, England), 134(15), 2783-2793 (2007-07-06)
The mechanism underlying the determination of neurotransmitter phenotype in the developing mesencephalon, particularly GABAergic versus glutamatergic fate, remains largely unknown. Here, we show in mice that the basic helix-loop-helix transcriptional repressor gene Helt (also known as Megane and Heslike) functions
Tomoya Nakatani et al.
The Journal of biological chemistry, 279(16), 16356-16367 (2004-02-07)
Neuronal differentiation is regulated by many basic-helix-loop-helix (bHLH) family transcriptional activators and repressors, and the balance of activity between these factors is important for the differentiation process. Here, we report the identification of a novel transcriptional repressor, designated Helt. Helt
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