免疫原
Synthetic peptide directed towards the N terminal region of human UXT
应用
Anti-UXT (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 2.5μg/ml.
生化/生理作用
Ubiquitously-expressed, prefoldin-like chaperone (UXT; ART-27) is a cofactor that modulates the androgen receptor-dependent transcription. It reportedly has roles in prostate cancer progression and induction of apoptosis by mitochondrial aggregation or TNF-induced pathway.
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
其他说明
Synthetic peptide located within the following region: MATPPKRRAVEATGEKVLRYETFISDVLQRDLRKVLDHRDKVYEQLAKYL
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Samir S Taneja et al.
The Journal of biological chemistry, 279(14), 13944-13952 (2004-01-09)
Androgen receptor trapped clone-27 (ART-27) is a newly described transcriptional coactivator that binds to the N terminus of the androgen receptor (AR). Given the vital importance of AR signaling in prostate growth and differentiation, we investigated the role of ART-27
Tijuana N Moss et al.
In vitro cellular & developmental biology. Animal, 43(3-4), 139-146 (2007-06-08)
Mitochondria are the bioenergetic and metabolic centers in eukaryotic cells and play a central role in apoptosis. Mitochondrial distribution is controlled by the microtubular cytoskeleton. The perinuclear aggregation of mitochondria is one of the characteristics associated with some types of
Yuefeng Huang et al.
Molecular biology of the cell, 22(8), 1389-1397 (2011-02-11)
Proteins that directly regulate tumor necrosis factor (TNF) signaling have critical roles in determining cell death and survival. Previously we characterized ubiquitously expressed transcript (UXT)-V2 as a novel transcriptional cofactor to regulate nuclear factor-κB in the nucleus. Here we report
Min Ji Yoon et al.
Nature communications, 12(1), 1955-1955 (2021-03-31)
p62/SQSTM1 is known to act as a key mediator in the selective autophagy of protein aggregates, or aggrephagy, by steering ubiquitinated protein aggregates towards the autophagy pathway. Here, we use a yeast two-hybrid screen to identify the prefoldin-like chaperone UXT
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持