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Merck
CN

B0507

Bradykinin potentiator B

≥97% (TLC)

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关于此项目

经验公式(希尔记法):
C56H91N15O13
化学文摘社编号:
分子量:
1182.41
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
250-374-6
MDL number:
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产品名称

Bradykinin potentiator B, ≥97% (TLC)

InChI key

JXGBFZMUUPNIBD-UHFFFAOYSA-N

InChI

1S/C56H91N15O13/c1-5-33(4)45(54(82)70-28-12-19-41(70)53(81)71-29-13-20-42(71)55(83)84)66-47(75)34(14-6-7-23-57)64-48(76)38-16-9-25-67(38)50(78)36(15-8-24-60-56(58)59)65-49(77)39-17-10-26-68(39)52(80)40-18-11-27-69(40)51(79)37(30-32(2)3)63-44(73)31-61-46(74)35-21-22-43(72)62-35/h32-42,45H,5-31,57H2,1-4H3,(H,61,74)(H,62,72)(H,63,73)(H,64,76)(H,65,77)(H,66,75)(H,83,84)(H4,58,59,60)

SMILES string

CCC(C)C(NC(=O)C(CCCCN)NC(=O)C1CCCN1C(=O)C(CCCNC(N)=N)NC(=O)C2CCCN2C(=O)C3CCCN3C(=O)C(CC(C)C)NC(=O)CNC(=O)C4CCC(=O)N4)C(=O)N5CCCC5C(=O)N6CCCC6C(O)=O

assay

≥97% (TLC)

form

solid

mol wt

~_1.2 kDa

storage temp.

−20°C

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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E B Sabia et al.
Journal of medicinal chemistry, 20(12), 1679-1681 (1977-12-01)
The structural requirements for prolonged residual ("sensitizing") activity in bradykinin-potentiating peptides (BPP's) were investigated through a study of seven synthetic BPP's including three not previously described: [Lys6]-BPP9a, [Gly6]potentiator B, and [Lys6,Gln8]potentiator B. The quantitation of the sensitizing activities in the
Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C.
H Kato et al.
Biochemistry, 10(6), 972-980 (1971-03-16)
M Tominaga et al.
Journal of medicinal chemistry, 18(2), 130-133 (1975-02-01)
In a study of the relationship between structure and activity of bradykinin potentiating peptides (BPP), six analogs and homologs of peptides occurring in the venoms of Bothrops jararaca and Agkistrodon halys blomhoffii were synthesized and assayed in the isolated guinea

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