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Merck
CN

B131

8-Bromoguanosine-3′,5′-cyclomonophosphate sodium salt

别名:

8-Br-cGMP

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关于此项目

经验公式(希尔记法):
C10H10BrN5NaO7P
化学文摘社编号:
分子量:
446.08
UNSPSC Code:
12352204
EC Number:
256-993-8
Beilstein/REAXYS Number:
8378760
MDL number:
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SMILES string

[Na+].NC1=Nc2c(nc(Br)n2[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C(=O)N1

storage temp.

−20°C

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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Zhijian Wang et al.
American journal of physiology. Renal physiology, 304(5), F543-F552 (2012-12-14)
We used the patch-clamp technique to examine the role of carbon monoxide (CO) in regulating Ca(2+)-activated big-conductance K (BK) channels in the principal cell of the cortical collecting duct (CCD). Application of CORM3 or CORM2, a CO donor, activated BK
Stephen M Downs
Molecular reproduction and development, 78(10-11), 778-794 (2011-09-29)
Cumulus cell-enclosed oocytes (CEO), denuded oocytes (DO), or dissected follicles were obtained 44-48 hr after priming immature mice (20-23 days old) with 5 IU or immature rats (25-27 days old) with 12.5 IU of equine chorionic gonadotropin, and exposed to a variety of
Praveen Shukla et al.
American journal of physiology. Heart and circulatory physiology, 303(12), H1418-H1425 (2012-10-23)
Melatonin inhibits nitric oxide (NO)-induced relaxation of coronary arteries. We tested the hypothesis that melatonin increases the phosphorylation of phosphodiesterase 5 (PDE5), which increases the activity of the enzyme and thereby decreases intracellular cGMP accumulation in response to NO and
N Kabbesh et al.
Veterinary journal (London, England : 1997), 192(3), 368-373 (2011-10-12)
The direct vasodilatory action of pentoxifylline (1-(5-oxohexyl)-3,7-dimethylxanthine) and its signalling pathway was evaluated in equine digital veins. Cumulative concentration-response curves to pentoxifylline (1 nM to 300 μM) were recorded in phenylephrine-precontracted equine digital vein rings under different experimental conditions. Relaxation
Karla Kretschmannova et al.
Molecular endocrinology (Baltimore, Md.), 26(1), 153-164 (2011-12-03)
Pituitary cells fire action potentials independently of external stimuli, and such spontaneous electrical activity is modulated by a large variety of hypothalamic and intrapituitary agonists. Here, we focused on the potential role of hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels in

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