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Merck
CN

B131

8-Bromoguanosine-3′,5′-cyclomonophosphate sodium salt

别名:

8-Br-cGMP

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关于此项目

经验公式(希尔记法):
C10H10BrN5NaO7P
化学文摘社编号:
分子量:
446.08
UNSPSC Code:
12352204
EC Number:
256-993-8
Beilstein/REAXYS Number:
8378760
MDL number:
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SMILES string

[Na+].NC1=Nc2c(nc(Br)n2[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C(=O)N1

storage temp.

−20°C

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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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N Kabbesh et al.
Veterinary journal (London, England : 1997), 192(3), 368-373 (2011-10-12)
The direct vasodilatory action of pentoxifylline (1-(5-oxohexyl)-3,7-dimethylxanthine) and its signalling pathway was evaluated in equine digital veins. Cumulative concentration-response curves to pentoxifylline (1 nM to 300 μM) were recorded in phenylephrine-precontracted equine digital vein rings under different experimental conditions. Relaxation
Karla Kretschmannova et al.
Molecular endocrinology (Baltimore, Md.), 26(1), 153-164 (2011-12-03)
Pituitary cells fire action potentials independently of external stimuli, and such spontaneous electrical activity is modulated by a large variety of hypothalamic and intrapituitary agonists. Here, we focused on the potential role of hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels in
Ljiljana Nikolić et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 198(7), 525-540 (2012-04-27)
The spontaneously active Br neuron from the brain-subesophageal ganglion complex of the garden snail Helix pomatia rhythmically generates regular bursts of action potentials with quiescent intervals accompanied by slow oscillations of membrane potential. We examined the involvement of the Na(+)/K(+)
Gabriela Bombarda et al.
Clinics (Sao Paulo, Brazil), 66(8), 1407-1412 (2011-09-15)
Results from our laboratory have demonstrated that intracerebroventricular administration of sildenafil to conscious rats promoted a noticeable increase in both lumbar sympathetic activity and heart rate, with no change in the mean arterial pressure. The intracerebroventricular administration of sildenafil may
Zhijian Wang et al.
American journal of physiology. Renal physiology, 304(5), F543-F552 (2012-12-14)
We used the patch-clamp technique to examine the role of carbon monoxide (CO) in regulating Ca(2+)-activated big-conductance K (BK) channels in the principal cell of the cortical collecting duct (CCD). Application of CORM3 or CORM2, a CO donor, activated BK

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