生物来源
mouse
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
BOB78, monoclonal
表单
buffered aqueous solution
分子量
antigen ~90 kDa
种属反应性
mouse, human, monkey
浓度
~1 mg/mL
技术
dot blot: suitable
flow cytometry: 1-2 μg/mL using 1x106 THP-1 cells treated with 3 μM camptothecin
immunocytochemistry: suitable
western blot: suitable
一般描述
The clearance of neutrophils that appear in large numbers at the inflammatory site is carried out by programmed cell death (apoptosis). An apoptotic neutrophil undergoes several changes in the amount of protein, carbohydrates and lipids. These changes are recognized by macrophages, which thus destroy the neutrophils by phagocytosis. BOB78, with a molecular mass of 90 kDa, is an up-regulated protein that appears in the granular compartment of the late apoptotic neutrophil. This protein does not appear in freshly isolated erythrocytes, platelets, lymphocytes, monocytes, or neutrophils.
免疫原
serum-deprived THP-1 cells.
应用
Monoclonal Anti-BOB78 antibody produced in mouse is suitable for use in several immunochemical techniques such as immunoblotting, immunocytochemistry, dot-blot and flow cytometry. Monoclonal antibodies specific for BOB78 are useful for studying the biology of apoptotic neutrophils.
外形
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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