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Merck
CN
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主要文件

B3685

Sigma-Aldrich

Monoclonal Anti-BOB78 antibody produced in mouse

clone BOB78, purified immunoglobulin, buffered aqueous solution

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About This Item

MDL编号:
UNSPSC代码:
12352203

生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

BOB78, monoclonal

表单

buffered aqueous solution

分子量

antigen ~90 kDa

种属反应性

mouse, human, monkey

浓度

~1 mg/mL

技术

dot blot: suitable
flow cytometry: 1-2 μg/mL using 1x106 THP-1 cells treated with 3 μM camptothecin
immunocytochemistry: suitable
western blot: suitable

一般描述

The clearance of neutrophils that appear in large numbers at the inflammatory site is carried out by programmed cell death (apoptosis). An apoptotic neutrophil undergoes several changes in the amount of protein, carbohydrates and lipids. These changes are recognized by macrophages, which thus destroy the neutrophils by phagocytosis. BOB78, with a molecular mass of 90 kDa, is an up-regulated protein that appears in the granular compartment of the late apoptotic neutrophil. This protein does not appear in freshly isolated erythrocytes, platelets, lymphocytes, monocytes, or neutrophils.

免疫原

serum-deprived THP-1 cells.

应用

Monoclonal Anti-BOB78 antibody produced in mouse is suitable for use in several immunochemical techniques such as immunoblotting, immunocytochemistry, dot-blot and flow cytometry. Monoclonal antibodies specific for BOB78 are useful for studying the biology of apoptotic neutrophils.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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