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Merck
CN

B4309

Sigma-Aldrich

Biocytinamide

别名:

Lys-(biotinyl)-NH2

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关于此项目

经验公式(希尔记法):
C16H29N5O3S
化学文摘社编号:
分子量:
371.50
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32
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表单

powder

储存温度

−20°C

SMILES字符串

N[C@@H](CCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(N)=O

InChI

1S/C16H29N5O3S/c17-10(15(18)23)5-3-4-8-19-13(22)7-2-1-6-12-14-11(9-25-12)20-16(24)21-14/h10-12,14H,1-9,17H2,(H2,18,23)(H,19,22)(H2,20,21,24)/t10-,11-,12-,14-/m0/s1

InChI key

BFTIPPVTTJTHLM-MNXVOIDGSA-N

应用

Fluorogenic reagent for specific C-terminal labeling of peptides and proteins by carboxypeptidase Y catalyzed transpeptidation reactions.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H R Stennicke et al.
Analytical biochemistry, 248(1), 141-148 (1997-05-15)
The ability to carry out specific C-terminal modification or labeling of peptides and proteins has a broad range of applications. It is well established that this may be achieved by protease-catalyzed transacylation reactions and that carboxypeptidase Y (CPD-Y) is suitable
Wenwen Duan et al.
Proteomics, 16(1), 60-69 (2015-11-11)
Caspase activation and proteolytic cleavages are the major events in the early stage of apoptosis. Identification of protein substrates cleaved by caspases will reveal the occurrence of the early events in the apoptotic process and may provide potential drug targets
Stefan Dengl et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(5), 1763-1779 (2015-02-12)
Humanized hapten-binding IgGs were designed with an accessible cysteine close to their binding pockets, for specific covalent payload attachment. Individual analyses of known structures of digoxigenin (Dig)- and fluorescein (Fluo) binding antibodies and a new structure of a biotin (Biot)-binder

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