B5182
7-Benzyloxyquinoline
≥99% (HPLC), solid
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关于此项目
经验公式（希尔记法）:
C16H13NO
化学文摘社编号:
分子量:
235.28
UNSPSC Code:
12161501
PubChem Substance ID:
MDL number:
InChI
1S/C16H13NO/c1-2-5-13(6-3-1)12-18-15-9-8-14-7-4-10-17-16(14)11-15/h1-11H,12H2
SMILES string
C(Oc1ccc2cccnc2c1)c3ccccc3
InChI key
SIDLHXXVIBTSJZ-UHFFFAOYSA-N
assay
≥99% (HPLC)
form
solid
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Fluorogenic substrate for CYP3A4.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Bikash Dangi et al.
Archives of biochemistry and biophysics, 698, 108677-108677 (2020-11-17)
We investigate the effect of the alcohol-induced increase in the content of CYP2E1 in human liver microsomes (HLM) on the function of CYP3A4. Membrane incorporation of the purified CYP2E1 into HLM considerably increases the rate of metabolism of 7-benzyloxyquinoline (BQ)
M N Lombardo et al.
Drug metabolism and disposition: the biological fate of chemicals, 47(9), 995-1003 (2019-06-16)
Pharmacokinetic/pharmacodynamic properties are strongly correlated with the in vivo efficacy of antibiotics. Propargyl-linked antifolates, a novel class of antibiotics, demonstrate potent antibacterial activity against both Gram-positive and Gram-negative pathogenic bacteria, including multidrug-resistant Staphylococcus aureus Here, we report our efforts to
Anup Aggarwal et al.
Cell, 170(2), 249-259 (2017-07-04)
Widespread resistance to first-line TB drugs is a major problem that will likely only be resolved through the development of new drugs with novel mechanisms of action. We have used structure-guided methods to develop a lead molecule that targets the
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