生物来源
human
重组
expressed in HEK 293 cells
方案
>95% (SDS-PAGE)
表单
lyophilized powder
分子量
~40 kDa by SDS-PAGE (reducing)
储存条件
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
溶解性
water: soluble
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... TNFRSF17(608)
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生化/生理作用
BCMA, a member of the TNF receptor superfamily, binds to the TNF ligands, APRIL and BAFF. It stimulates the production of IgM in peripheral blood B cells and increases survival of cultured B cells.
Member of the TNF receptor superfamily; binds to the TNF ligands, APRIL and BAFF; stimulates the production of IgM in peripheral blood B cells and increases survival of cultured B cells.
The extracellular domain (amino acids 2-54) of human BCMA is fused to the Fc portion of human IgG.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
分析说明
Inhibits BAFF- and April-mediated B cell activation. May be used to detect cell surface BAFF by flow cytometry.
法规信息
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