B7935
Anti-BACE-2, N-terminus (43-60) antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-Asp1, Anti-DRAP (Down region aspartic protease), Anti-Memapsin 1
生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
浓度
~1 mg/mL
技术
indirect immunofluorescence: 2-4 μg/mL using HEK293 cells transfected with human BACE-2
western blot: 0.5-1 μg/mL using whole extract of human HEK293 cells transfected with human BACE-2
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... BACE2(25825)
免疫原
synthetic peptide corresponding to amino acids 43-60 near the N-terminus of human BACE-2.
生化/生理作用
The immunogen sequence is specific for BACE-2 and is not found in BACE-1 homolog.
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
B D Bennett et al.
The Journal of biological chemistry, 275(27), 20647-20651 (2000-04-06)
Beta-site amyloid precursor protein cleaving enzyme (BACE) is a novel transmembrane aspartic protease that possesses all the known characteristics of the beta-secretase involved in Alzheimer's disease (Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P.
Guriqbal Basi et al.
The Journal of biological chemistry, 278(34), 31512-31520 (2003-06-13)
The deposition of extracellular beta-amyloid peptide (A beta) in the brain is a pathologic feature of Alzheimer's disease. The beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), an integral membrane aspartyl protease responsible for cleavage of amyloid precursor protein (APP)
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