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关于此项目
经验公式(希尔记法):
C19H23N4O6PS
化学文摘社编号:
分子量:
466.45
NACRES:
NA.79
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
245-013-4
MDL number:
assay
≥98% (TLC)
Quality Level
form
powder or crystals
color
white to off-white
storage temp.
2-8°C
SMILES string
Cc1ncc(CN(C=O)\C(C)=C(/CCOP(O)(O)=O)SC(=O)c2ccccc2)c(N)n1
InChI
1S/C19H23N4O6PS/c1-13(23(12-24)11-16-10-21-14(2)22-18(16)20)17(8-9-29-30(26,27)28)31-19(25)15-6-4-3-5-7-15/h3-7,10,12H,8-9,11H2,1-2H3,(H2,20,21,22)(H2,26,27,28)/b17-13+
InChI key
BTNNPSLJPBRMLZ-GHRIWEEISA-N
General description
S-苯甲酰基硫胺 O-单磷酸酯(苯磷硫胺)是两亲性 S-酰基硫胺衍生物。是一种脂溶性维生素。苯磷硫胺含噻唑环。与硫胺素相比,苯磷硫胺具有更高的生物利用度。
Application
S-苯甲酰基硫胺 O-单磷酸酯用于确定其对大鼠骨骼肌缺血和再灌注的影响。
Biochem/physiol Actions
S-苯甲酰基硫胺 O-单磷酸酯(苯磷硫胺)是一种治疗剂。有助于预防视网膜病变、神经病变和肾脏病变等糖尿病并发症。苯磷硫胺抑制糖尿病患者糖基化终末产物(AGE)的合成。苯磷硫胺被认为是预防糖尿病神经病变的营养保健产品。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Xiaoli Pan et al.
Neuroscience bulletin, 32(6), 591-596 (2016-10-04)
To date, we still lack disease-modifying therapies for Alzheimer's disease (AD). Here, we report that long-term administration of benfotiamine improved the cognitive ability of patients with AD. Five patients with mild to moderate AD received oral benfotiamine (300 mg daily) over
Alaa Alkhalaf et al.
Diabetes care, 33(7), 1598-1601 (2010-04-24)
To investigate the effect of benfotiamine on urinary albumin excretion (UAE) and the tubular damage marker kidney injury molecule-1 (KIM-1) in patients with type 2 diabetes and nephropathy. Patients with type 2 diabetes and UAE equivalent to 15-300 mg/24 h
Rajesh Katare et al.
Journal of molecular and cellular cardiology, 49(4), 625-638 (2010-06-15)
Benfotiamine (BFT) is a transketolase activator that directs glucose to the pentose phosphate pathway. The present study investigated whether BFT improves the recovery after myocardial infarction (MI) and explored underlying mechanisms of protection. Non-diabetic and streptozotocin-induced type 1 diabetic mice
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B9636-250MG | 04061833443866 |