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Merck
CN

B9803

Sigma-Aldrich

Bone Morphogenetic Protein 5 human

recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, >95% (SDS-PAGE)

别名:

BMP-5

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关于此项目

MDL编号:
UNSPSC代码:
51111800
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生物来源

human

重组

expressed in NSO cells

方案

>95% (SDS-PAGE)

表单

lyophilized powder

分子量

subunit calculated mol wt ~18 kDa

储存条件

avoid repeated freeze/thaw cycles

技术

cell culture | mammalian: suitable

杂质

endotoxin, tested

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... BMP5(653)

生化/生理作用

Cellular responses to BMP-5 is mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors.

外形

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile, 0.1% TFA, with 5% trehalose and 50 μg of BSA per 1 μg of cytokine

分析说明

The biological activity is measured by its ability to induce alkaline phosphatase production in ATDC5 chondrogenic cells.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T Ebendal et al.
Journal of neuroscience research, 51(2), 139-146 (1998-02-20)
Transforming growth factors-beta (TGF-betas), activins, and bone morphogenetic proteins (BMPs) comprise an evolutionarily well-conserved group of proteins controlling a number of cell differentiation, cell growth, and morphogentic processes during development. The superfamily of TGFbeta-related genes include over 25 members in
A H Reddi
Nature biotechnology, 16(3), 247-252 (1998-04-07)
Morphogenesis is the developmental cascade of pattern formation and body plan establishment, culminating in the adult form. It has formed the basis for the emerging discipline of tissue engineering, which uses principles of molecular developmental biology and morphogenesis gleaned through
M Kawabata et al.
Cytokine & growth factor reviews, 9(1), 49-61 (1998-08-28)
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which are members of the transforming growth factor-beta (TGF-beta) superfamily. Activities of BMPs are extracellularly regulated by BMP-binding proteins, Noggin and Chordin. BMPs bind to two different types of serine-threonine kinase receptors, type
Elina V García et al.
Theriogenology, 84(4), 589-599 (2015-05-28)
Previous studies have reported that bone morphogenetic protein 5 (BMP5) is differentially expressed in the isthmus of bovine oviducts and it is present in the oviductal fluid. However, the specific action of this factor is unknown. To evaluate whether BMP5
Zhu Xishan et al.
Journal of experimental & clinical cancer research : CR, 30, 47-47 (2011-05-04)
Overwhelming evidence from leukemia research has shown that the clonal population of neoplastic cells exhibits marked heterogeneity with respect to proliferation and differentiation. There are rare stem cells within the leukemic population that possess extensive proliferation and self-renewal capacity not

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