B9804
抗-Bcl-2抗体，小鼠单克隆
clone 10C4, purified from hybridoma cell culture
别名:
Anti-BCL-2
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关于此项目
Conjugate:
unconjugated
Clone:
10C4, monoclonal
Application:
ARR, WB
Citations:
11
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
10C4, monoclonal
form
buffered aqueous solution
mol wt
antigen 26 kDa
species reactivity
rat, mouse
concentration
~2 mg/mL
technique(s)
microarray: suitable, western blot: 2-10 μg/mL using rat osteosarcoma ROS cell extract
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
mouse ... Bcl2(12043)
rat ... Bcl2(24224)
Immunogen
对应于小鼠Bcl-2序列中61-76位氨基酸的合成肽，其与KLH偶联。
Biochem/physiol Actions
抗体识别的表位位于小鼠Bcl-2蛋白的氨基酸61-76内。
Physical form
磷酸盐缓冲盐水溶液，pH 7.4，含有15 mM叠氮化钠
Preparation Note
若需连续使用，可在2-8℃下保存最长一个月。若需延长储存时间，可将溶液分装并冷冻。 不建议反复冻融或存放在“无霜”冰柜中。如果长期储存时出现轻微浑浊，请在使用前通过离心澄清溶液。若工作稀释样品在12小时内未使用完，则应丢弃。
Disclaimer
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Beclin 1 Interacts With Active Caspase-3 and Bax in Oocytes From Atretic Follicles in the Rat Ovary.
María L Escobar et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 67(12), 873-889 (2019-10-05)
Oocyte cell death is a normal process in the mammalian ovary during follicular growth. Recent reports have demonstrated the presence of pro-apoptotic and pro-autophagic proteins during oocyte elimination. The goal of this study was to identify the interactions between proteins
Wanqi Huang et al.
Cell death & disease, 13(1), 17-17 (2021-12-22)
Impaired autophagy and excessive apoptosis disrupt cellular homeostasis and contribute to neural tube defects (NTDs), which are a group of fatal and disabling birth defects caused by the failure of neural tube closure during early embryonic development. However, the regulatory
Yue Li et al.
Molecular therapy. Nucleic acids, 35(2), 102163-102163 (2024-03-28)
Anorectal malformations (ARMs) are congenital diseases that lead to postoperative fecal incontinence, constipation, and soiling, despite improvements in surgery; however, their pathological mechanisms remain unclear. Here, we report the role of microRNA-141-3p in maintaining homeostasis between apoptosis and autophagy in
Elena Piegari et al.
Scientific reports, 10(1), 12250-12250 (2020-07-25)
Cardiotoxicity remains a serious problem in anthracycline-treated oncologic patients. Therapeutic modulation of microRNA expression is emerging as a cardioprotective approach in several cardiovascular pathologies. MiR-34a increased in animals and patients exposed to anthracyclines and is involved in cardiac repair. In
Wenfei Zhao et al.
Oncology letters, 18(5), 4613-4620 (2019-10-16)
The present study aimed to investigate the association between microRNA-152 and cisplatin resistance in non-small cell lung cancer. A549 and cisplatin-resistant A549 cells (A549/cis) were maintained in vitro. Reverse transcription-quantitative PCR (RT-qPCR) was performed to analyze differences in microRNA-152 levels
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