生物来源
mouse
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
10C4, monoclonal
表单
buffered aqueous solution
分子量
antigen 26 kDa
种属反应性
rat, mouse
浓度
~2 mg/mL
技术
microarray: suitable
western blot: 2-10 μg/mL using rat osteosarcoma ROS cell extract
同位素/亚型
IgG1
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
mouse ... Bcl2(12043)
rat ... Bcl2(24224)
免疫原
对应于小鼠Bcl-2序列中61-76位氨基酸的合成肽，其与KLH偶联。
生化/生理作用
抗体识别的表位位于小鼠Bcl-2蛋白的氨基酸61-76内。
外形
磷酸盐缓冲盐水溶液，pH 7.4，含有15 mM叠氮化钠
制备说明
若需连续使用，可在2-8℃下保存最长一个月。若需延长储存时间，可将溶液分装并冷冻。 不建议反复冻融或存放在“无霜”冰柜中。如果长期储存时出现轻微浑浊，请在使用前通过离心澄清溶液。若工作稀释样品在12小时内未使用完，则应丢弃。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Beclin 1 Interacts With Active Caspase-3 and Bax in Oocytes From Atretic Follicles in the Rat Ovary.
María L Escobar et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 67(12), 873-889 (2019-10-05)
Oocyte cell death is a normal process in the mammalian ovary during follicular growth. Recent reports have demonstrated the presence of pro-apoptotic and pro-autophagic proteins during oocyte elimination. The goal of this study was to identify the interactions between proteins
Wanqi Huang et al.
Cell death & disease, 13(1), 17-17 (2021-12-22)
Impaired autophagy and excessive apoptosis disrupt cellular homeostasis and contribute to neural tube defects (NTDs), which are a group of fatal and disabling birth defects caused by the failure of neural tube closure during early embryonic development. However, the regulatory
Yue Li et al.
Molecular therapy. Nucleic acids, 35(2), 102163-102163 (2024-03-28)
Anorectal malformations (ARMs) are congenital diseases that lead to postoperative fecal incontinence, constipation, and soiling, despite improvements in surgery; however, their pathological mechanisms remain unclear. Here, we report the role of microRNA-141-3p in maintaining homeostasis between apoptosis and autophagy in
Wenfei Zhao et al.
Oncology letters, 18(5), 4613-4620 (2019-10-16)
The present study aimed to investigate the association between microRNA-152 and cisplatin resistance in non-small cell lung cancer. A549 and cisplatin-resistant A549 cells (A549/cis) were maintained in vitro. Reverse transcription-quantitative PCR (RT-qPCR) was performed to analyze differences in microRNA-152 levels
Elena Piegari et al.
Scientific reports, 10(1), 12250-12250 (2020-07-25)
Cardiotoxicity remains a serious problem in anthracycline-treated oncologic patients. Therapeutic modulation of microRNA expression is emerging as a cardioprotective approach in several cardiovascular pathologies. MiR-34a increased in animals and patients exposed to anthracyclines and is involved in cardiac repair. In
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