BM0010
Ifetroban sodium
≥98% (HPLC)
别名:
2-[[(1S,2R,3S,4R)-3-[4-[(Pentylamino)carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]methyl]-benzenepropanoic acid sodium salt, BMS 180291-02, BMS-180291 sodium, Sodium ifetroban
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关于此项目
经验公式（希尔记法）:
C25H31N2O5 · Na
化学文摘社编号:
分子量:
462.51
PubChem Substance ID:
UNSPSC Code:
12352200
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: 20 mg/mL, clear
storage temp.
room temp
SMILES string
[O-]C(CCC1=C(C[C@H]2[C@@H](O3)CC[C@@H]3[C@H]2C4=NC(C(NCCCCC)=O)=CO4)C=CC=C1)=O.[Na+]
InChI
1S/C25H32N2O5.Na/c1-2-3-6-13-26-24(30)19-15-31-25(27-19)23-18(20-10-11-21(23)32-20)14-17-8-5-4-7-16(17)9-12-22(28)29;/h4-5,7-8,15,18,20-21,23H,2-3,6,9-14H2,1H3,(H,26,30)(H,28,29);/q;+1/p-1/t18-,20-,21+,23-;/m0./s1
InChI key
WOHSQDNIXPEQAE-QBKVZTCDSA-M
Biochem/physiol Actions
Ifetroban (BMS-180291) is a potent and selective thromboxane receptor antagonist.
Ifetroban (BMS-180291) is a potent and selective thromboxane receptor antagonist. The IC50 for inhibition of arachadonate or U-46619-induced platelet aggregation in human plasma is 7 nM and 30 nM, respectively. Ifetroban inhibits platelet aggregation in African green monkey 100% at 3 mpk, and blocks the contractile effects of U-46619 and Ang II in rabbit renal afferent arterioles.
Features and Benefits
Ifetroban is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.
Legal Information
Sold for research purposes only under agreement from BMS.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| BM0010-5MG | 04061832784373 |
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