Anti-phospho-Cdk1 (pThr¹⁴/pTyr¹⁵) antibody produced in rabbit

Cdk1 is a regulatory protein that stimulates mitosis in eukaryotic cells. Phosphorylation of Thr14 and Tyr15 residues in Cdk1 causes its inactivation, which eventually results in the exit of cells from the mitotic cycle. Cdk1 may also be in involved in protein SUMOylation during cell cycle regulation . Anti-phospho-Cdk1 (p(Thr¹⁴)/p(Tyr¹⁵)) antibody is specific for rat, human and mouse Cdk1 (p(Thr¹⁴)/p(Tyr¹⁵)) and other cyclin-dependent kinases that are phosphorylated on these amino acid residues. The antibody does not bind with Cdk6 or Cdk4.

synthetic phosphopeptide derived from the region of the human cdk (cyclin-dependent kinases) that contains threonine 14 and tyrosine 15.

Anti-phospho-Cdk1 (p(Thr¹⁴)/p(Tyr¹⁵)) antibody is suitable for use in western blot (1:1,000), immunoblot (35kDa) and immunoprecipitation (1:100).

Solution in Dulbecco′s phosphate buffered saline (without Mg²⁺ and Ca²⁺), containing 50% glycerol with 1.0 mg/mL bovine serum albumin and 0.05% sodium azide.

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