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Merck
CN

C0297

Sigma-Aldrich

Monoclonal Anti-Caldesmon antibody produced in mouse

clone C21, ascites fluid

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MDL编号:
UNSPSC代码:
12352203
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生物来源

mouse

偶联物

unconjugated

抗体形式

ascites fluid

抗体产品类型

primary antibodies

克隆

C21, monoclonal

包含

15 mM sodium azide

种属反应性

mammals

技术

indirect ELISA: 1:2,500
western blot: suitable

同位素/亚型

IgG1

运输

dry ice

储存温度

−20°C

基因信息

human ... CALD1(800)
mouse ... Cald1(109624)
rat ... Cald1(25687)

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免疫原

chicken caldesmon

生化/生理作用

The antibody is directed against an epitope near the carboxy-terminus, Ca2+/calmodulin and F-actin binding site of caldesmon. Using ELISA, the antibody is able to inhibit caldesmon binding to Ca2+/calmodulin and F-actin. By immunoblotting, the antibody shows broad species reactivity to non-muscle caldesmon of mammalian cells.

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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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J J Lin et al.
Hybridoma, 7(3), 273-288 (1988-06-01)
Monoclonal antibodies, C2, C9, C18, C21 and C23, against chicken gizzard caldesmon have been prepared and characterized. These antibodies reacted with gizzard caldesmon (150 KDa) by enzyme-linked immunosorbent assay and protein immunoblotting. Immunofluorescence microscopy with these antibodies on cultured gizzard
Julie L Boerner et al.
Oncogene, 22(43), 6679-6689 (2003-10-14)
Mutations within members of the EGF/ErbB receptor family frequently release the oncogenic potential of these receptors, resulting in the activation of downstream signaling events independent of ligand regulatory constraints. We previously have demonstrated that the signal transduction events originating from
Erik Y Zhang et al.
The American journal of pathology, 164(2), 601-612 (2004-01-27)
Partial bladder outlet obstruction (PBOO) induces remodeling of urinary bladder smooth muscle (detrusor). We demonstrate an increase in bladder wall mass, muscle bundle size, and a threefold increase in the cross-sectional area of detrusor myocytes following PBOO in male New
Makoto Hosoya et al.
BioMed research international, 2016, 1781894-1781894 (2016-07-13)
Deafness is one of the most common types of congenital impairments, and at least half of the cases are caused by hereditary mutations. Mutations of the gene KIAA1199 are associated with progressive hearing loss. Its expression is abundant in human
A Draeger et al.
FEBS letters, 291(1), 24-28 (1991-10-07)
Two-dimensional gel analysis of basic proteins in developing human smooth muscle identifies calponin as a prominent marker of the differentiated phenotype. Adult tissue (human and mouse) typically expresses up to four calponin isoforms, three of which appear sequentially during fetal

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