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Merck
CN

C0788

Z-Leu-Leu-Glu β-萘酰胺

≥98%, powder

别名:

Cbz-LLE β-naphthylamine

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关于此项目

经验公式(希尔记法):
C35H44N4O7
化学文摘社编号:
分子量:
632.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Assay:
≥98%
Form:
powder
Quality level:
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Quality Level

assay

≥98%

form

powder

color

white

solubility

THF: 25 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)Nc2ccc3ccccc3c2

InChI

1S/C35H44N4O7/c1-22(2)18-29(38-34(44)30(19-23(3)4)39-35(45)46-21-24-10-6-5-7-11-24)33(43)37-28(16-17-31(40)41)32(42)36-27-15-14-25-12-8-9-13-26(25)20-27/h5-15,20,22-23,28-30H,16-19,21H2,1-4H3,(H,36,42)(H,37,43)(H,38,44)(H,39,45)(H,40,41)

InChI key

MIYHULQEZFNUGE-UHFFFAOYSA-N

General description

Substrate for the glutamylpeptidyl-peptide hydrolase activity of the 20S proteasome (multicatalytic proteinase complex).


pictograms

Health hazard

signalword

Warning

hcodes

pcodes

Hazard Classifications

Carc. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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分析证书(COA)

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H Djaballah et al.
Biochemistry, 31(16), 4133-4141 (1992-04-28)
The multicatalytic proteinase (MCP) complex or proteasome is a major nonlysosomal proteinase of eukaryotic cells. The proteinase can cleave peptide bonds on the carboxyl side of hydrophobic, basic, or acidic amino acid residues. These activities have been referred to as
C Cardozo
Enzyme & protein, 47(4-6), 296-305 (1993-01-01)
The multicatalytic proteinase complex (MPC), also called the proteasome, is a ubiquitous particle (19S) that is required for life. It is found in the cytoplasm and nucleus of all eukaryotic cells where it degrades selected cytosolic and nuclear proteins. It
C Realini et al.
The Journal of biological chemistry, 272(41), 25483-25492 (1997-11-05)
Full-length cDNAs for three human proteasome activator subunits, called REGalpha, REGbeta, and REGgamma, have been expressed in Escherichia coli, and the purified recombinant proteins have been characterized. Recombinant alpha or gamma subunits form heptameric species; recombinant beta subunits are found



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货号GTIN
C0788-50MG04061832269801
C0788-10MG04061833260654
C0788-25MG04061833260661