C0845
6Ckine from mouse
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
别名:
Exodus-2, SLC
生物来源
mouse
重组
expressed in E. coli
方案
≥98% (HPLC)
≥98% (SDS-PAGE)
表单
lyophilized powder
分子量
16-17 kDa by SDS-PAGE
包装
pkg of 25 μg
储存条件
avoid repeated freeze/thaw cycles
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
UniProt登记号
储存温度
−20°C
基因信息
mouse ... Ccl21a(18829), Ccl21b(20298)
生化/生理作用
The expression of mouse 6Ckine has been detected at high levels in the spleen and lung. Recombinant mouse 6Ckine chemotattracts in vitro thymocytes and activated T-cells.
外形
Lyophilized with no additives.
分析说明
The biological activity is measured by its ability to chemoattract total murine T cell population.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Long Chen et al.
Molecular cancer, 12(1), 153-153 (2013-12-07)
Secondary lymphoid tissue chemokine (SLC) is a key CC chemokine for chemotaxis of immune cells and has been an attractive candidate for anti-tumor treatments. However, among the immune cells recruited by SLC to tumors, the CD25+ Foxp3+ regulatory T cells
Alexei Y Savinov et al.
The Journal of experimental medicine, 197(5), 643-656 (2003-03-05)
Activated insulin-specific CD8(+) T cells (IS-CD8(+) cells) home to the pancreas, destroy beta cells, and cause rapid diabetes upon transfer into diabetes-prone NOD mice. Surprisingly, they also cause diabetes in mouse strains that are free of preexistent inflammation. Thus, we
W Weninger et al.
The Journal of experimental medicine, 194(7), 953-966 (2001-10-03)
It has been proposed that two different antigen-experienced T cell subsets may be distinguishable by their preferential ability to home to lymphoid organs (central memory cells) or nonlymphoid tissues (effector memory/effector cells). We have shown recently that murine antigen-primed CD8(+)
Sherven Sharma et al.
Molecular cancer, 2, 22-22 (2003-05-13)
SLC/CCL21, normally expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts T cells and dendritic cells (DC). We have previously shown that SLC/CCL21-mediated anti-tumor responses are accompanied by significant induction of IFNgamma
Rilun Li et al.
Molecular biology reports, 40(10), 5615-5623 (2013-10-01)
To explore the anti-tumor effect and immune mechanism mediated by a new recombinant adeno-associated virus (rAAV) encoding secondary lymphoid tissue chemokine (SLC) mature peptide gene. AAV Helper-Free system was used for rAAV-SLC package. The anti-tumor effect of SLC was detected
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