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Merck
CN

C145

2-Chloroadenosine triphosphate tetrasodium hydrate

solid, ≥90% (HPLC)

别名:

2-Chloro-ATP tetrasodium hydrate, 2-Chloroadenosine 5′-triphosphate tetrasodium hydrate

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经验公式(希尔记法):
C10H11ClN5Na4O13P3 · xH2O
分子量:
629.55 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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SMILES string

O.[Na+].[Na+].[Na+].[Na+].Nc1nc(Cl)nc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O

assay

≥90% (HPLC)

form

solid

storage condition

desiccated

color

white

solubility

H2O: soluble

εmax

17,800 at 273 nm in methanol, 20,900 at 215 nm in methanol

storage temp.

−20°C

Biochem/physiol Actions

P2Y purinoceptor agonist.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Neuro-modulatory roles of purine nucleosides and nucleotides: their receptors and ligands.
Williams, et al.
Neurotransmissions, 6 (1990)
Three new adenosine triphosphate analogs. Synthesis and effects on isolated gut.
G R Gough et al.
Journal of medicinal chemistry, 16(10), 1188-1190 (1973-10-01)
G Burnstock et al.
British journal of pharmacology, 79(4), 907-913 (1983-08-01)
ATP, 2-chloro-ATP, 2-methylthio-ATP, and their unnatural L-enantiomers, were synthesized and their effects tested on the guinea-pig taenia coli and urinary bladder, and the stimulated frog ventricle. The potent P2-purinoceptor agonists, 2-chloro-ATP and 2-methylthio-ATP were, respectively, 30 and 200 times more

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