biological source
algae (marine)
form
powder
quality
Non-gelling
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General description
角叉菜胶是来自红藻细胞壁的粘多糖。 它们是由1，3α-1，4β-半乳聚糖组成的阴离子线性聚合物，每个二糖单元含有一个（κ-），两个（ι-）或三个（λ-）硫酸盐。 在离子溶液中，κ-和ι-角叉菜胶自缔合成螺旋结构，分别形成刚性或柔性凝胶。 λ-角叉菜胶不形成螺旋，并且不凝胶化。 角叉菜胶在商业上用作增稠剂和稳定剂。
Application
角叉菜胶被用来抑制体内和体外的免疫反应，其机制被认为涉及对巨噬细胞的选择性细胞病变作用。 由于ι-、κ-和λ-角叉菜胶具有不同程度的硫酸化，因此可以对它们在保护性、抗病毒性和免疫抑制活性方面的差异进行比较研究。
Non-gelling carrageenan is used to induce inflammation and inflammatory pain in the rodent hindpaw or air pouch models. More recently carrageenan has been injected directly into the joints of rodents to model arthritic pain and inflammation.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
植物油/植物胶产品
此项目有
A D Sedgwick et al.
Agents and actions, 18(3-4), 439-446 (1986-06-01)
A comparative assessment of the time course of changes in three models of acute carrageenan-induced inflammation, the six-day air pouch, polyester sponge and pleurisy models, was obtained by measuring exudate volume, leucocyte numbers, PGE2 concentrations and lactate dehydrogenase activity at
A F Gabriel et al.
Journal of neuroscience methods, 163(1), 9-16 (2007-03-27)
Experimental pain research is often complicated by the absence of an objective and detailed method to analyze behavioral changes. In the present study, acute pain was induced into the right knee of the rat (n=15) through the injection of 2mg
A W Thomson
Biomedicine / [publiee pour l'A.A.I.C.I.G.], 28(3), 148-152 (1978-05-01)
Since the biological effects of carrageenan were reviewed in 1972 by Di Rosa it has become clear from a large number of reports that this algal polysaccharide markedly influences immune responses. Profound suppression of immunity evidenced by impaired antibody production
Immunopharmacology of the macrophage-toxic agent carrageenan.
A W Thomson et al.
International journal of immunopharmacology, 1(4), 247-261 (1979-01-01)
Samuel M Cohen et al.
Critical reviews in toxicology, 32(5), 413-444 (2002-10-23)
Carrageenan is a high-molecular-weight, strongly anionic polymer derived from several species of red seaweed that is used for the textural stabilization of foods. Processed Eucheuma Seaweed (PES) is a form of carrageenan with a higher cellulose content. Food-grade carrageenan has
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