C2604
Compound 52
≥98.0%, powder
别名:
2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine, NG-52
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关于此项目
经验公式（希尔记法）:
C16H19ClN6O
化学文摘社编号:
分子量:
346.81
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥98.0%
form
powder
color
white to off-white
solubility
methylene chloride: 50 mg/mL, clear, colorless
shipped in
dry ice
storage temp.
−20°C
SMILES string
CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NCCO)nc12
Biochem/physiol Actions
2,6,9-substituted purine inhibitor of cyclin-dependent kinases.
Wen-Liang Wang et al.
Acta pharmacologica Sinica, 42(4), 633-640 (2020-08-02)
Inhibition of glycolysis process has been an attractive approach for cancer treatment due to the evidence that tumor cells are more dependent on glycolysis rather than oxidative phosphorylation pathway. Preliminary evidence shows that inhibition of phosphoglycerate kinase 1 (PGK1) kinase
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