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Merck
CN

C265

Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse

clone 6G9, purified immunoglobulin, buffered aqueous solution

别名:

Anti-CAMKA, Anti-CaMKIINalpha, Anti-CaMKIIalpha, Anti-MRD53, Anti-MRT63

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.44
MDL number:
Conjugate:
unconjugated
Clone:
6G9, monoclonal
Application:
indirect immunofluorescence
western blot
Species reactivity:
rat, mouse
Citations:
19
Technique(s):
indirect immunofluorescence: suitable using rat hippocampus
western blot: 0.5-1.0 μg/mL
Uniprot accession no.:
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产品名称

Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse, clone 6G9, purified immunoglobulin, buffered aqueous solution

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

6G9, monoclonal

form

buffered aqueous solution

mol wt

antigen ~50 kDa

species reactivity

rat, mouse

technique(s)

indirect immunofluorescence: suitable using rat hippocampus
western blot: 0.5-1.0 μg/mL

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

rat ... Camk2a(25400)

Application

Monoclonal Anti-CaM Kinase IIα (CaMKIIα) antibody produced in mouse has been used in immunohistochemistry and western blotting.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

CaM Kinase II α is a Ca2+/calmodulin-dependent kinase that belongs to the serine/threonine protein kinases family. It facilitates the regulation of NMDAR-dependent AMPA receptor trafficking to the synapses. Mouse anti-CaM kinase II α antibody reacts specifically with phosphorylated and non-phosphorylated forms of native and recombinant CaM (Ca2+/calmodulin-dependent) kinase II α subunit in rats. The product has shown no reactivity for phosphorylated or non-phosphorylated β subunit (60kD).

Immunogen

partially purified rat CaM kinase II.

Physical form

Solution in phosphate buffered saline containing 0.05% sodium azide

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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ke-Hui Hu et al.
Behavioural brain research, 359, 81-88 (2018-10-27)
Ischemic stroke is a major cause of disability and mortality worldwide, while no unequivocally efficacious drug is currently available to treat post-stroke functional impairments. Animal and clinical investigations suggest that the motor cortex stimulation constitutes a particularly promising approach for
Activity-dependent neuroplasticity induced by an enriched environment reverses cognitive deficits in scribble deficient mouse
Hilal ML, et al.
Cerebral Cortex, 27(12), 5635-5651 (2016)
Metabotropic signal transduction for bradykinin in submucosal neurons of guinea pig small intestine
Hu HZ, et al.
Journal of Pharmacology and Experimental Therapeutics, 309(1), 310-319 (2004)
Naohiro Kon et al.
Genes & development, 28(10), 1101-1110 (2014-05-17)
Daily behavioral rhythms in mammals are governed by the central circadian clock, located in the suprachiasmatic nucleus (SCN). The behavioral rhythms persist even in constant darkness, with a stable activity time due to coupling between two oscillators that determine the
Guang-Yan Wu et al.
Cerebral cortex (New York, N.Y. : 1991), 28(11), 3753-3763 (2017-10-03)
The medial prefrontal cortex (mPFC) is closely involved in many higher-order cognitive functions, including learning to associate temporally discontiguous events (called temporal associative learning). However, direct evidence for the role of mPFC and the neural pathway underlying modulation of temporal

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