C3093
Chloroethylclonidine 二盐酸盐
别名:
2-[2,6-Dichloro(N-β-chloroethyl-N-methyl)-4-aminomethyl]phenylimino-2-imidazolidine dihydrochloride, CEC dihydrochloride
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关于此项目
经验公式（希尔记法）:
C13H17Cl3N4 · 2HCl
化学文摘社编号:
分子量:
408.58
UNSPSC Code:
12352200
MDL number:
InChI key
CZSAXNDACBPMAB-UHFFFAOYSA-N
InChI
1S/C13H17Cl3N4.2ClH/c1-20(5-2-14)8-9-6-10(15)12(11(16)7-9)19-13-17-3-4-18-13;;/h6-7H,2-5,8H2,1H3,(H2,17,18,19);2*1H
SMILES string
Cl.Cl.CN(CCCl)Cc1cc(Cl)c(\N=C2/NCCN2)c(Cl)c1
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Application
Irreversible α1b adrenergic alkylating agent
Biochem/physiol Actions
Irreversible α1B-adrenoceptor alkylating agent.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
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M Takanashi et al.
Naunyn-Schmiedeberg's archives of pharmacology, 343(6), 669-673 (1991-06-01)
The influence of the alpha 1b-adrenoceptor-selective antagonist chlorethylclonidine on the alpha 1-adrenergic positive inotropic effect and the phosphoinositide hydrolysis induced by phenylephrine was investigated in the rabbit ventricular myocardium. Pretreatment of membrane fractions derived from the rabbit ventricular muscle with
Yoav Litvin et al.
The European journal of neuroscience, 40(2), 2344-2351 (2014-05-28)
Research suggests a causal link between estrogens and mood. Here, we began by examining the effects of estradiol (E2 ) on rat innate and conditioned defensive behaviors in response to cat odor. Second, we utilized whole-cell patch clamp electrophysiological techniques
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