C3242
CDKi hydrochloride
≥98% (HPLC), solid
别名:
2,4-Diamino-5-oxo-pyrimidine hydrochloride
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关于此项目
经验公式（希尔记法）:
C4H6N4O · xHCl
化学文摘社编号:
分子量:
126.12 (free base basis)
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥98% (HPLC)
form
solid
solubility
H2O: 21 mg/mL
storage temp.
2-8°C
SMILES string
Cl[H].Nc1ncc(O)c(N)n1
InChI
1S/C4H6N4O.ClH/c5-3-2(9)1-7-4(6)8-3;/h1,9H,(H4,5,6,7,8);1H
InChI key
KEFSYBXFZWLDQU-UHFFFAOYSA-N
Biochem/physiol Actions
CDKi hydrochloride is a potent and selective ATP competitiive inhibitor of cycB-CDK1, cycE-CDK2, and cycD1-CDK4. Demonstrates significant inhibitory activity against a variety of tumor type both in vitro and in vivo.
Features and Benefits
This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves