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Merck
CN

C3490

Cyclofenil

≥98% (HPLC), white, solid

别名:

4,4′-Cyclohexylidenemethylenediphenol, 4-(Cyclohexylidenemethylene)-bis-phenol

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关于此项目

经验公式(希尔记法):
C23H24O4
化学文摘社编号:
分子量:
364.43
UNSPSC Code:
51111800
PubChem Substance ID:
EC Number:
220-089-1
MDL number:
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InChI key

GVOUFPWUYJWQSK-UHFFFAOYSA-N

InChI

1S/C23H24O4/c1-16(24)26-21-12-8-19(9-13-21)23(18-6-4-3-5-7-18)20-10-14-22(15-11-20)27-17(2)25/h8-15H,3-7H2,1-2H3

SMILES string

CC(=O)Oc1ccc(cc1)\C(=C2\CCCCC2)c3ccc(OC(C)=O)cc3

assay

≥98% (HPLC)

form

solid

color

white

solubility

DMSO: ≥10 mg/mL

storage temp.

2-8°C

Gene Information

Biochem/physiol Actions

Cyclofenil is a selective estrogen receptor β antagonist.

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T C Li et al.
British journal of obstetrics and gynaecology, 99(12), 1008-1013 (1992-12-01)
To examine the effect of two anti-oestrogens, clomiphene citrate and cyclofenil, on endometrial morphology in the luteal phase. A prospective, randomised, cross-over study. Jessop Hospital for Women, Sheffield, UK. 10 women who were previously fertile and regularly cycling. The administration
Wagner F Pacheco et al.
Talanta, 74(5), 1442-1449 (2008-03-29)
In this work, a fluorimetric approach for the determination of cyclofenil, 4-4'-(cyclohexylidenemethylene)bis(phenylacetate), is presented. The method was based on the intense fluorescence (250/410 nm) observed after a UV photochemical treatment of cyclofenil. The influence of the pH and solvent system
J Pope et al.
The Cochrane database of systematic reviews, (2)(2), CD000955-CD000955 (2000-05-05)
To assess the effects and toxicity of Cyclofenil versus placebo for the treatment of Raynaud's phenomenon (RP) in scleroderma. We searched the Cochrane Controlled Trials Register, and Medline up to 1996 using the Cochrane Collaboration search strategy developed by Dickersin
Sung Hoon Kim et al.
Organic letters, 10(21), 4931-4934 (2008-10-10)
We have synthesized a new SNAPFL analogue (1) that exhibits a large Stokes shift (78 nm) (abs. 542 nm, em. 620 nm) and a good quantum yield. Because of the large overlap between the emission spectrum of 1 and the
D Drecktrah et al.
Journal of cell science, 111 ( Pt 7), 951-965 (1998-05-20)
Previous studies have shown that the Golgi stack and the trans-Golgi network (TGN) may play a role in capturing escaped resident endoplasmic reticulum (ER) proteins, and directing their retrograde transport back to that organelle. Whether this retrograde movement represents a

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