C4241
Anti-Corticotropin-Releasing Factor Receptor 2 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-CRFR2
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4 μg/mL using human pituitary tissue
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CRHR2(1395)
mouse ... Crhr2(12922)
rat ... Crhr2(64680)
Immunogen
synthetic peptide corresponding to the extracellular N-terminal domain of human corticotropin-releasing factor receptor, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.
Physical form
Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Shaaban A Mousa et al.
Molecular neurobiology, 58(11), 5459-5472 (2021-08-01)
Corticotropin-releasing factor (CRF) orchestrates our body's response to stressful stimuli. Pain is often stressful and counterbalanced by activation of CRF receptors along the nociceptive pathway, although the involvement of the CRF receptor subtypes 1 and/or 2 (CRF-R1 and CRF-R2, respectively)
Shaaban A Mousa et al.
Journal of neuroinflammation, 19(1), 148-148 (2022-06-16)
Under inflammatory conditions, the activation of corticotropin-releasing factor (CRF) receptor has been shown to inhibit pain through opioid peptide release from immune cells or neurons. CRF's effects on human and animal pain modulation depend, however, on the distribution of its
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