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Merck
CN

C5021

Sigma-Aldrich

Acetylcholinesterase 来源于牛红细胞

Type XII-S, lyophilized powder, 0.25-1.0 unit/mg solid

别名:

AChE, Acetylcholine Esterase, membrane-bound, 来源于牛红细胞, Acetylcholine acetylhydrolase

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类型

Type XII-S

表单

lyophilized powder

比活

0.25-1.0 unit/mg solid

UniProt登记号

储存温度

−20°C

基因信息

cow ... ACHE(540446)

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生化/生理作用

Major degradative enzyme for acetylcholine in vivo. Converts acetylcholine + H2O to choline + acetic acid.

外形

Lyophilized powder containing phosphate buffer salts

分析说明

The activity obtained using acetylcholine as substrate is 30-100 times that obtained with butyrylcholine, using acetylcholinesterase from electric eel.

其他说明

Activity believed to be membrane (stroma) bound.
One unit will hydrolyze 1.0 μmole of acetylcholine to choline and acetate per min at pH 8.0 at 37 °C.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mariah L Scott et al.
Journal of the American Mosquito Control Association, 28(4), 323-326 (2013-02-12)
Insecticide resistance to organophosphates and carbamates can be the result of changes in acetylcholinesterase activity conferred by the ACE-1 mutation. Detection of this altered target site mutation is important in guiding informed decisions for resistance management. In this study we
Colonic perforation in a case of adult Hirschsprung's disease with acetylcholinesterase-negative neuronal fibers.
Naruhiko Ikoma et al.
The American surgeon, 79(3), E130-E132 (2013-03-07)
Heng Luo et al.
Journal of microbiology and biotechnology, 23(2), 161-166 (2013-02-16)
At present, acetylcholinesterase (AChE) inhibitors are the first group of drugs to treat mild to moderate Alzheimer's disease (AD). Although beneficial in improving cognitive and behavioral symptoms, the effectiveness of AChE inhibitors has been questioned since they do not delay
Marc W van der Kamp et al.
Biochemistry, 52(16), 2708-2728 (2013-04-06)
Computational enzymology is a rapidly maturing field that is increasingly integral to understanding mechanisms of enzyme-catalyzed reactions and their practical applications. Combined quantum mechanics/molecular mechanics (QM/MM) methods are important in this field. By treating the reacting species with a quantum
Michael R Reddy et al.
The American journal of tropical medicine and hygiene, 88(5), 897-907 (2013-02-27)
Anti-malaria interventions that rely on insecticides can be compromised by insecticide-resistance alleles among malaria vectors. We examined frequency changes of resistance alleles at two loci, knockdown resistance (kdr) and acetylcholinesterase-1 (ace-1), which confer resistance to pyrethroids and DDT, and carbamates

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