Anti-CAMK2B (30-44) antibody produced in rabbit

CAMKII/CAMK2 (Calcium/calmodulin-dependent protein kinase type II) is expressed from a family of four genes, α, β, γ, and δ. CAMK2B is highly expressed in barin tissue.

synthetic peptide corresponding to amino acids 30-44 of human CAMK2B.

Anti-CAMK2B (30-44) antibody produced in rabbit for western blot at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Calcium/calmodulin-dependent protein kinase (CAMK) activates in the calcium-triggered CaMKK-CaMK1 signaling cascade. It regulates transcription activators, cell cycle, hormone production, cell differentiation, actin filament organization and neurite outgrowth, upon calcium influx. CAMK controls axonal extension and growth cone motility in hippocampal and cerebellar nerve cells. It is vital for proper activation of cyclin-D1/CDK4 complex during G1 progression in diploid fibroblasts. It also plays a role in K+ and ANG2-mediated regulation of the aldosterone synthase (CYP11B2) to produce aldosterone in the adrenal cortex. CAMKII/CAMK2 is the main CAMK in human skeletal muscle. CAMK2B promoter is methylated in breast cancer cell lines.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

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