跳转至内容
Merck
CN

C5367

Sigma-Aldrich

Monoclonal Anti-Casein Kinase 2α antibody produced in mouse

~2 mg/mL, clone 1AD9, purified immunoglobulin, buffered aqueous solution

别名:

Anti-CK2α

登录查看公司和协议定价

选择尺寸


关于此项目

MDL编号:
UNSPSC代码:
12352203
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

1AD9, monoclonal

表单

buffered aqueous solution

分子量

antigen ~35 kDa

种属反应性

rat, mouse, human

浓度

~2 mg/mL

技术

immunoprecipitation (IP): suitable
indirect ELISA: suitable
microarray: suitable
western blot: 2-4 μg/mL using total cell extract of MCF7 cells.

同位素/亚型

IgG1

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... CSNK2A1(1457)
mouse ... Csnk2a1(12995)
rat ... Csnk2a1(116549)

一般描述

CK2 is a ubiquitously expressed serine/threonine kinase that has been implicated in various cellular functions such as cell death, cell cycle regulation, and mRNA synthesis. This protein kinase comprises of two catalytic α subunits and two dimeric β subunits that associate to form a heterotetrameric enzyme complex.CK2 is also involved in regulating viral infections . Monoclonal Anti-Casein Kinase 2α antibody is specific for casein kinase 2 α in humans, rats and mice (approx. 35 kDa). The antibody-binding epitope resides within amino acids 319-324 of human CK2α. This epitope is conserved across several species.

免疫原

human denatured recombinant casein kinase 2α.

应用

Monoclonal Anti-Casein Kinase 2α antibody is suitable for use in immunoprecipitation and western blot assays using human fibroblasts . The product can also be used for indirect ELISA and microarray applications.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

N A St-Denis et al.
Cellular and molecular life sciences : CMLS, 66(11-12), 1817-1829 (2009-04-24)
Protein kinase CK2 is a serine/threonine kinase with a multitude of protein substrates. The enzyme is ubiquitously expressed in mammalian cells, where it functions in a variety of cellular processes, including cell cycle progression, apoptosis, transcription, and viral infection. While
Yang Gao et al.
Journal of virology, 82(1), 96-104 (2007-10-26)
Human cytomegalovirus (HCMV) UL84 is a phosphoprotein that shuttles from the nucleus to the cytoplasm and is required for oriLyt-dependent DNA replication and viral growth. UL84 was previously shown to interact with IE2 (IE86) in infected cells, and this interaction
Inessa Ermakova et al.
Journal of molecular biology, 330(5), 925-934 (2003-07-16)
Protein kinase CK2 (formerly called: casein kinase 2) is a heterotetrameric enzyme composed of two separate catalytic chains (CK2alpha) and a stable dimer of two non-catalytic subunits (CK2beta). CK2alpha is a highly conserved member of the superfamily of eukaryotic protein

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持