C5492
CIL-102
≥95% (HPLC), solid
别名:
1-[4-(Furo[2,3-b]quinolin-4-ylamino)phenyl]ethanone
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关于此项目
经验公式（希尔记法）:
C19H14N2O2
化学文摘社编号:
分子量:
302.33
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥95% (HPLC)
表单
solid
溶解性
DMSO: 12 mg/mL
运输
wet ice
储存温度
−20°C
SMILES字符串
CC(=O)c1ccc(Nc2c3ccccc3nc4occc24)cc1
InChI
1S/C19H14N2O2/c1-12(22)13-6-8-14(9-7-13)20-18-15-4-2-3-5-17(15)21-19-16(18)10-11-23-19/h2-11H,1H3,(H,20,21)
InChI key
VJDPGTFIMDGXDQ-UHFFFAOYSA-N
生化/生理作用
CIL-102 is a tubulin polymerization inhibitor: apoptosis inducer.
法律信息
US Patent No. 6,750,223. Sold for non-human research purposes under a non-exclusive license agreement with Kaohsiung Medical University.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Wen-Shih Huang et al.
PloS one, 12(1), e0168989-e0168989 (2017-01-10)
CIL-102 (1-[4-(furo[2,3-b]quinolin-4-ylamino)phenyl]ethanone) is a well-known, major active agent of the alkaloid derivative of Camptotheca acuminata with valuable biological properties, including anti-tumorigenic activity. In this study, we investigated the molecular mechanisms by which CIL-102 mediated the induction of cell death, and
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