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C5862

CD30/Fc Chimera human

Name: CD30/Fc Chimera human
Brand: SIGMA

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

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关于此项目

UNSPSC Code:

12352200

MDL number:

MFCD03702817

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recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

100-110 kDa by SDS-PAGE (reducing), calculated mol wt 66 kDa

impurities

endotoxin, tested

UniProt accession no.

P28908

storage temp.

−20°C

Gene Information

human ... TNFRSF8(943)

General description

The extracellular domain of human CD30/Fc Chimera (amino acids 1-379) is fused to the C-terminal Fc domain of human IgG.

Biochem/physiol Actions

CD30, a type I transmembrane glycoprotein, is a member of the TNF receptor family. CD30 has a crucial role in the pathophysiology of Hodgkin′s disease and other CD30⁺lymphomas. The ligand for CD30 is CD30 ligand (CD30L). CD30-CD30L interaction mediates cell proliferation, cell activation, cell differentiation, and cell death.

CD30, a type I transmembrane glycoprotein, is a member of the TNF receptor family; mediates cell proliferation, cell activation, cell differentiation, and cell death.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by its ability to neutralize recombinant human CD30 ligand on HDLM-2 cells, a Hodgkin′s lymphoma cell line.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

092K1568

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