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Merck
CN

C6170

伴刀豆球蛋白A 来源于洋刀豆 (刀豆)

agarose conjugate, Type V-B, buffered aqueous suspension

别名:

刀豆素 A

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化学文摘社编号:
UNSPSC Code:
12161501
MDL number:
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conjugate

agarose conjugate

type

Type V-B

form

buffered aqueous suspension

extent of labeling

~15 mg per mL

matrix

4% beaded agarose

matrix activation

p-nitrophenyl chloroformate

matrix spacer

1 atom

capacity

~6 mg/mL binding capacity (yeast mannan)

storage temp.

2-8°C

Biochem/physiol Actions

刀豆素 A 无血型特异性,但对末端 α-D-甘露糖基和 α-D-葡糖基残基具有亲和力。需要 Ca2+ 和 Mn2+ 离子存在才能显示活性。刀豆素 A 在 pH 6.5 或更低的条件下解离为二聚体。pH 在 5.8 至 7.0 之间时,刀豆素 A 以四聚体形式存在;pH 高于 7.0 时,形成更高的聚合体。根据聚合程度不同,刀豆素 A 可能显示出具有促有丝分裂的活性。琥珀酰化可以生成一种能够在 pH 高于 5.6 时仍保持二聚体形式的活性二聚体。

Physical form

Suspension in 0.1 M acetate buffer, pH 6.0, containing 1 M NaCl, 1 mM each Mn2+, Mg2+, and Ca2+, and 0.02% thimerosal

Analysis Note

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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