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经验公式(希尔记法):
C16H17N3O5S
化学文摘社编号:
分子量:
363.39
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
表单
powder or crystals
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C2=O)C(O)=O
InChI
1S/C16H17N3O5S/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24)/t10-,11-,15-/m1/s1
InChI key
BOEGTKLJZSQCCD-UEKVPHQBSA-N
一般描述
Cefadroxil is a broad spectrum cephalosporin antibiotic, widely used in veterinery medicine for the oral treatment of infectious diseases.
应用
Cefadroxil has been used as a standard in the analysis of cefadroxil residues in the samples of domestic sheep milk using penzym enzymatic test method. Cefadroxil may be used as an analytical reference standard for the quantification of the analyte in milk samples using Delvotest photometric technique and in biological samples using high-performance liquid chromatography, respectively.
Cefadroxil has been used as a standard in the analysis of cefadroxil residues in the samples of domestic sheep milk using penzym enzymatic test method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语:
Danger
危险分类
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
Eunice Kazue Kano et al.
Arzneimittel-Forschung, 58(1), 42-47 (2008-03-29)
Two different cefadroxil (CAS 50370-12-2) formulations were evaluated for their relative bioavailability in 24 healthy volunteers who received a single 500 mg oral dose of each preparation. An open, randomized clinical trial designed as a two-period crossover study with a
Robert Six et al.
Journal of the American Veterinary Medical Association, 233(3), 433-439 (2008-08-05)
To evaluate the efficacy and safety of administration of cefovecin, compared with cefadroxil, for treatment of naturally occurring secondary superficial pyoderma, abscesses, and infected wounds in dogs. Multicenter, randomized, positive-controlled clinical trial. 235 client-owned dogs. Dogs with clinical signs of
G Lamba et al.
The West Indian medical journal, 60(3), 346-348 (2012-01-10)
We report a life-threatening anaphylactic reaction to cefadroxil in a 60-year old female with no previous history of allergies to penicillins. Cefadroxil is a first-generation cephalosporin and anaphylactic reactions to it in patients with no previous history of penicillin allergy
Scleredema following scabies infestation.
Amit K Malhotra et al.
Pediatric dermatology, 25(1), 136-138 (2008-02-29)
Mohamed A Kamal et al.
Drug metabolism and pharmacokinetics, 23(4), 236-242 (2008-09-03)
Pept2 knockout mice are an important tool to evaluate the evolving role and relevance of this proton-coupled oligopeptide transporter beyond drug disposition, where the transporter also modulates the pharmacodynamic and toxicodynamic effects of drug substrates. Our in vivo studies with
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