表单
solid
分子量
apparent mol wt 514.6
一般描述
Cefpirome is a bactericidal antibiotic, which belongs to the fourth generation of cephalosporins. It shows a broad spectrum of activity against gram positive and gram negative bacteria.
应用
4th generation cephalosporin antibacterial.
Cefpirome may be used as a reference standard in the determination of cefpirome in pharmaceutical formulations and human plasma samples using reversed phase high performance liquid chromatography (RP-HPLC).
Cefpirome may be used as a reference standard in the determination of cefpirome in pharmaceutical formulations and human plasma samples using reversed phase high performance liquid chromatography (RP-HPLC).
Juliana F Roos et al.
Intensive care medicine, 33(5), 781-788 (2007-03-08)
To develop a population pharmacokinetics model for cefpirome in ICU patients, to assess pharmacokinetic-pharmacodynamic profiles vs. MIC distribution of likely ICU pathogens, and to assess their expected cumulative fraction of response (CFR). Prospective observational study in a multidisciplinary ICU. Twelve
Alejandro Beceiro et al.
The Journal of antimicrobial chemotherapy, 66(9), 2006-2010 (2011-07-12)
Two clinical isolates of Escherichia coli, EC18 and EC21, were non-susceptible (MICs 4-16 mg/L) to cefpirome and cefepime, with marked synergy with clavulanate, yet were susceptible to cefotaxime and ceftazidime (MICs ≤ 1 mg/L). EC19, from the same patient as
C C Wagner et al.
International journal of clinical pharmacology and therapeutics, 47(3), 178-186 (2009-03-14)
Knowledge on the elimination of antibiotics by extracorporeal hemofiltration is a prerequisite for appropriate antimicrobial dosing in patients with renal failure. The present study set out to determine the clearance of the novel lipopetide antibiotic daptomycin from human whole blood
Cristina Tuchiluş et al.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 110(2), 465-467 (2007-09-07)
Cefpirome and cefepime possess a greater antibacterial spectrum in vitro than third-generation cephalosporins because they are active against Enterobacteriaceae, which produce beta-lactamases, which may inactivate third-generation cephalosporins. The aim of this study was to quantitatively compare the in vitro activity
Simultaneous quantification of cefpirome and cetirizine or levocetirizine in pharmaceutical formulations and human plasma by RP-HPLC.
Journal of Analytical Chemistry, 63(9), 881-887 (2008)
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