form
solid
storage temp.
−20°C
SMILES string
CC(C)C[C@@H](C(N[C@H](C(OC)=O)CC(C)C)=O)NC(OCC1=CC=CC=C1)=O
InChI
1S/C21H32N2O5/c1-14(2)11-17(19(24)22-18(12-15(3)4)20(25)27-5)23-21(26)28-13-16-9-7-6-8-10-16/h6-10,14-15,17-18H,11-13H2,1-5H3,(H,22,24)(H,23,26)/t17-,18-/m0/s1
InChI key
FYKHRTVYUNLJLJ-ROUUACIJSA-N
Biochem/physiol Actions
N-CBZ-Ieu-Ieu methyl ester, an N-terminal and C-terminal blocked dipeptide, and related molecules may be useful in analysis of proteosome proteases.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
S Yamada et al.
Zoological science, 15(3), 353-357 (2008-05-10)
The 20S proteasome of eukaryotic cells has at least three distinct peptidase activities (trypsin-like, chymotrypsin-like and peptidylglutamylpeptide (PGP) hydrolase activities). These peptidases are latent and require appropriate activators. SDS has been widely used as an activator of these peptidases, but
R C Gardner et al.
The Biochemical journal, 346 Pt 2, 447-454 (2000-03-24)
Proteasomes are large multisubunit proteinases which have several distinct catalytic sites. In this study a series of di- and tri-peptidyl boronic acids have been tested on the chymotrypsin-like activity of purified mammalian 20 S and 26 S proteasomes assayed with
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