生物来源
mouse
偶联物
unconjugated
抗体形式
ascites fluid
抗体产品类型
primary antibodies
克隆
K4.62, monoclonal
包含
15 mM sodium azide
种属反应性
human
技术
indirect immunofluorescence: 1:20 using frozen human tissue sections
同位素/亚型
IgG1
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... KRT19(3880)
免疫原
cytoskeletal proteins from the cultured human breast carcinoma cell line MCF-7
应用
Monoclonal Anti-Cytokeratin 4.62 antibody produced in mouse is suitable for indirect immunofluorescence at a dilution of 1:20 using frozen human tissue sections.
生化/生理作用
Cytokeratins are proteins of keratin-containing intermediate filaments that provide mechanical support and other additional functions in epithelial cells. It is found in the intracytoplasmic cytoskeleton of epithelial tissue. Epithelial tissue expresses cytokeratin subunits in a specific and stable pattern. Cytokeratins along with vimentin are involved in cell proliferation, migration and differentiation of preodontoblasts and preameloblasts. The intermediate-sized filaments are abundant in human endothelial cells and are mostly of vimentin type.
Reacts with cytokeratin polypeptide 19. The antibody labels the basal layer of non-keratinizing epithelium, metaplastic epithelium of the cervix, simple epithelium, transitional epithelium, squamous cell carcinomas and adenocarcinomas expressing cytokeratin 19.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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